4hj2
From Proteopedia
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- | {{STRUCTURE_4hj2| PDB=4hj2 | SCENE= }} | ||
- | ===Crystal Structure Analysis of GSTA1-1 in complex with chlorambucil=== | ||
- | {{ABSTRACT_PUBMED_23460799}} | ||
- | == | + | ==Crystal Structure Analysis of GSTA1-1 in complex with chlorambucil== |
- | [[http://www.uniprot.org/uniprot/GSTA1_HUMAN GSTA1_HUMAN | + | <StructureSection load='4hj2' size='340' side='right'caption='[[4hj2]], [[Resolution|resolution]] 2.10Å' scene=''> |
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[4hj2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HJ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HJ2 FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LZ6:L-GAMMA-GLUTAMYL-S-(2-{[4-(3-CARBOXYPROPYL)PHENYL](2-CHLOROETHYL)AMINO}ETHYL)-L-CYSTEINYLGLYCINE'>LZ6</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hj2 OCA], [https://pdbe.org/4hj2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hj2 RCSB], [https://www.ebi.ac.uk/pdbsum/4hj2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hj2 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/GSTA1_HUMAN GSTA1_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.<ref>PMID:20606271</ref> | ||
- | == | + | ==See Also== |
- | [[ | + | *[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]] |
- | + | == References == | |
- | == | + | <references/> |
- | <references | + | __TOC__ |
- | + | </StructureSection> | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Chiniadis L]] |
- | [[Category: | + | [[Category: Karpusas M]] |
- | [[Category: | + | [[Category: Labrou NE]] |
- | + |
Current revision
Crystal Structure Analysis of GSTA1-1 in complex with chlorambucil
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