4am8

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{{STRUCTURE_4am8| PDB=4am8 | SCENE= }}
 
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===Crystal structure of the R54G mutant of putrescine transcarbamylase from Enterococcus faecalis bound to a curing guanidinium ion===
 
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==Function==
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==Crystal structure of the R54G mutant of putrescine transcarbamylase from Enterococcus faecalis bound to a curing guanidinium ion==
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[[http://www.uniprot.org/uniprot/PTC_ENTFA PTC_ENTFA]] Catalyzes the phosphorolysis of N-carbamoylputrescine to form carbamoyl phosphate and putrescine. Is involved in the degradation pathway of the polyamine agmatine. Also has weak activity with ornithine and cadaverine.<ref>PMID:4621632</ref>
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<StructureSection load='4am8' size='340' side='right'caption='[[4am8]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4am8]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AM8 FirstGlance]. <br>
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[[4am8]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AM8 OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAI:GUANIDINE'>GAI</scene>, <scene name='pdbligand=GLN:GLUTAMINE'>GLN</scene>, <scene name='pdbligand=ILE:ISOLEUCINE'>ILE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=PAO:N-(PHOSPHONOACETYL)-L-ORNITHINE'>PAO</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4am8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4am8 OCA], [https://pdbe.org/4am8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4am8 RCSB], [https://www.ebi.ac.uk/pdbsum/4am8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4am8 ProSAT]</span></td></tr>
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<references group="xtra"/><references/>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PTC_ENTFA PTC_ENTFA] Catalyzes the phosphorolysis of N-carbamoylputrescine to form carbamoyl phosphate and putrescine. Is involved in the degradation pathway of the polyamine agmatine. Also has weak activity with ornithine and cadaverine.<ref>PMID:4621632</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Enterococcus faecalis]]
[[Category: Enterococcus faecalis]]
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[[Category: Putrescine carbamoyltransferase]]
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[[Category: Large Structures]]
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[[Category: Polo, L M.]]
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[[Category: Polo LM]]
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[[Category: Rubio, V.]]
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[[Category: Rubio V]]
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[[Category: Agmatine deiminase route]]
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[[Category: Arginine deiminase]]
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[[Category: Ornithine carbamoyltransferase]]
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[[Category: Palo]]
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[[Category: Phosphonoacetylornithine]]
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[[Category: Transferase]]
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Current revision

Crystal structure of the R54G mutant of putrescine transcarbamylase from Enterococcus faecalis bound to a curing guanidinium ion

PDB ID 4am8

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