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4igz
From Proteopedia
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| - | {{STRUCTURE_4igz| PDB=4igz | SCENE= }}
| + | #REDIRECT [[5vei]] This PDB entry is obsolete and replaced by 5vei |
| - | ===Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2===
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| - | ==Function==
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| - | [[http://www.uniprot.org/uniprot/SRBS2_HUMAN SRBS2_HUMAN]] Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.<ref>PMID:9211900</ref><ref>PMID:12475393</ref> | + | |
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| - | ==About this Structure==
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| - | [[4igz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IGZ OCA].
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| - | ==Reference==
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| - | <references group="xtra"/><references/>
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| - | [[Category: Homo sapiens]]
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| - | [[Category: Arrowsmith, C H.]]
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| - | [[Category: Bakkouri, M El.]]
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| - | [[Category: Bountra, C.]]
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| - | [[Category: Edwards, A M.]]
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| - | [[Category: Gu, J.]]
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| - | [[Category: Huang, H.]]
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| - | [[Category: Liu, K.]]
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| - | [[Category: Liu, Y.]]
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| - | [[Category: Min, J.]]
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| - | [[Category: SGC, Structural Genomics Consortium.]]
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| - | [[Category: Sidhu, S S.]]
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| - | [[Category: Tempel, W.]]
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| - | [[Category: Protein binding]]
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| - | [[Category: Sgc]]
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| - | [[Category: Sh3]]
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| - | [[Category: Src homology 3 domain]]
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| - | [[Category: Structural genomics consortium]]
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Current revision
- REDIRECT 5vei This PDB entry is obsolete and replaced by 5vei