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3iwt

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{{STRUCTURE_3iwt| PDB=3iwt | SCENE= }}
 
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===Structure of hypothetical molybdenum cofactor biosynthesis protein B from Sulfolobus tokodaii===
 
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{{ABSTRACT_PUBMED_20054111}}
 
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==About this Structure==
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==Structure of hypothetical molybdenum cofactor biosynthesis protein B from Sulfolobus tokodaii==
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[[3iwt]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii Sulfolobus tokodaii]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2pjk 2pjk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IWT OCA].
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<StructureSection load='3iwt' size='340' side='right'caption='[[3iwt]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3iwt]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii Sulfurisphaera tokodaii]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2pjk 2pjk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IWT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IWT FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iwt OCA], [https://pdbe.org/3iwt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iwt RCSB], [https://www.ebi.ac.uk/pdbsum/3iwt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iwt ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q96Y52_SULTO Q96Y52_SULTO]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iw/3iwt_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3iwt ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The structure of a probable Mo-cofactor biosynthesis protein B from Sulfolobus tokodaii, belonging to space group P6(4)22 with unit-cell parameters a = b = 136.68, c = 210.52 A, was solved by molecular replacement to a resolution of 1.9 A and refined to an R factor and R(free) of 16.8% and 18.5%, respectively. The asymmetric unit contains a trimer, while the biologically significant oligomer is predicted to be a hexamer by size-exclusion chromatography. The subunit structure and fold of ST2315 are similar to those of other enzymes that are known to be involved in the molybdopterin- and molybdenum cofactor-biosynthesis pathways.
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==Reference==
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Structure of hypothetical Mo-cofactor biosynthesis protein B (ST2315) from Sulfolobus tokodaii.,Antonyuk SV, Strange RW, Ellis MJ, Bessho Y, Kuramitsu S, Shinkai A, Yokoyama S, Hasnain SS Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Dec 1;65(Pt, 12):1200-3. Epub 2009 Nov 27. PMID:20054111<ref>PMID:20054111</ref>
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<ref group="xtra">PMID:020054111</ref><references group="xtra"/><references/>
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[[Category: Sulfolobus tokodaii]]
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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[[Category: Antonyuk, S V.]]
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</div>
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[[Category: Bessho, Y.]]
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<div class="pdbe-citations 3iwt" style="background-color:#fffaf0;"></div>
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[[Category: Ellis, M J.]]
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== References ==
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[[Category: Hasnain, S S.]]
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<references/>
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[[Category: Kuramitsu, S.]]
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__TOC__
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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</StructureSection>
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[[Category: Strange, R W.]]
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[[Category: Large Structures]]
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[[Category: Yokoyama, S.]]
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[[Category: Sulfurisphaera tokodaii]]
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[[Category: Biosynthesis]]
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[[Category: Antonyuk SV]]
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[[Category: Molybdenum cofactor]]
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[[Category: Bessho Y]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Ellis MJ]]
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[[Category: Nppsfa]]
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[[Category: Hasnain SS]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Kuramitsu S]]
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[[Category: Rsgi]]
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[[Category: Strange RW]]
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[[Category: Structural genomic]]
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[[Category: Yokoyama S]]
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[[Category: Unknown function]]
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Current revision

Structure of hypothetical molybdenum cofactor biosynthesis protein B from Sulfolobus tokodaii

PDB ID 3iwt

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