3iqt

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{{STRUCTURE_3iqt| PDB=3iqt | SCENE= }}
 
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===Structure of the HPT domain of Sensor protein barA from Escherichia coli CFT073.===
 
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==Function==
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==Structure of the HPT domain of Sensor protein barA from Escherichia coli CFT073.==
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[[http://www.uniprot.org/uniprot/BARA_ECOL6 BARA_ECOL6]] Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay (By similarity).
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<StructureSection load='3iqt' size='340' side='right'caption='[[3iqt]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[3iqt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_CFT073 Escherichia coli CFT073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IQT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IQT FirstGlance]. <br>
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[[3iqt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IQT OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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[[Category: Escherichia coli]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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[[Category: Histidine kinase]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iqt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iqt OCA], [https://pdbe.org/3iqt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iqt RCSB], [https://www.ebi.ac.uk/pdbsum/3iqt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iqt ProSAT]</span></td></tr>
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[[Category: Cuff, M E.]]
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</table>
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[[Category: Freeman, L.]]
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== Function ==
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[[Category: Joachimiak, A.]]
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[https://www.uniprot.org/uniprot/BARA_ECOL6 BARA_ECOL6] Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay (By similarity).
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[[Category: Kim, Y.]]
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== Evolutionary Conservation ==
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Rakowski, E.]]
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Check<jmol>
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[[Category: Atp-binding]]
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<jmolCheckbox>
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[[Category: Cell inner membrane]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iq/3iqt_consurf.spt"</scriptWhenChecked>
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[[Category: Cell membrane]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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[[Category: Histidine phosphotransfer domain]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Htp]]
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</jmolCheckbox>
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[[Category: Kinase]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3iqt ConSurf].
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[[Category: Mcsg]]
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<div style="clear:both"></div>
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[[Category: Membrane]]
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__TOC__
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[[Category: Midwest center for structural genomic]]
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</StructureSection>
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[[Category: Nucleotide-binding]]
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[[Category: Escherichia coli CFT073]]
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[[Category: Phosphoprotein]]
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[[Category: Large Structures]]
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[[Category: Protein structure initiative]]
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[[Category: Cuff ME]]
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[[Category: Psi-2]]
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[[Category: Freeman L]]
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[[Category: Structural genomic]]
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[[Category: Joachimiak A]]
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[[Category: Transcription]]
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[[Category: Kim Y]]
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[[Category: Transcription regulation]]
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[[Category: Rakowski E]]
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[[Category: Transferase]]
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[[Category: Transmembrane]]
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[[Category: Two-component regulatory system]]
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Current revision

Structure of the HPT domain of Sensor protein barA from Escherichia coli CFT073.

PDB ID 3iqt

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