3jra
From Proteopedia
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| - | {{STRUCTURE_3jra| PDB=3jra | SCENE= }} | ||
| - | ===Crystal structure of Fis bound to 27bp non consensus sequence DNA F6=== | ||
| - | {{ABSTRACT_PUBMED_20395367}} | ||
| - | == | + | ==Crystal structure of Fis bound to 27bp non consensus sequence DNA F6== |
| - | [[http://www.uniprot.org/uniprot/FIS_ECOLI FIS_ECOLI | + | <StructureSection load='3jra' size='340' side='right'caption='[[3jra]], [[Resolution|resolution]] 3.11Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3jra]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JRA FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.11Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jra OCA], [https://pdbe.org/3jra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jra RCSB], [https://www.ebi.ac.uk/pdbsum/3jra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jra ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FIS_ECOLI FIS_ECOLI] Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin-mediated DNA inversion. Prevents initiation of DNA replication from oriC.<ref>PMID:2209559</ref> <ref>PMID:8836178</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jr/3jra_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jra ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[FIS protein|FIS protein]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| - | [[Category: Escherichia coli | + | </StructureSection> |
| - | + | [[Category: Escherichia coli K-12]] | |
| - | + | [[Category: Large Structures]] | |
| - | + | [[Category: Cascio D]] | |
| - | + | [[Category: Johnson RC]] | |
| - | + | [[Category: Stella S]] | |
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Current revision
Crystal structure of Fis bound to 27bp non consensus sequence DNA F6
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