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3jtj

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{{STRUCTURE_3jtj| PDB=3jtj | SCENE= }}
 
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===3-deoxy-manno-octulosonate cytidylyltransferase from Yersinia pestis===
 
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==About this Structure==
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==3-deoxy-manno-octulosonate cytidylyltransferase from Yersinia pestis==
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[[3jtj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTJ OCA].
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<StructureSection load='3jtj' size='340' side='right' caption='[[3jtj]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3jtj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis_co92 Yersinia pestis co92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JTJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">kdsB, y2772, YPO1400, YP_1193 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=214092 Yersinia pestis CO92])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-deoxy-manno-octulosonate_cytidylyltransferase 3-deoxy-manno-octulosonate cytidylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.38 2.7.7.38] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jtj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jtj OCA], [http://pdbe.org/3jtj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3jtj RCSB], [http://www.ebi.ac.uk/pdbsum/3jtj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3jtj ProSAT], [http://www.topsan.org/Proteins/CSGID/3jtj TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/KDSB_YERPE KDSB_YERPE]] Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jt/3jtj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jtj ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: 3-deoxy-manno-octulosonate cytidylyltransferase]]
[[Category: 3-deoxy-manno-octulosonate cytidylyltransferase]]
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[[Category: Yersinia pestis]]
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[[Category: Yersinia pestis co92]]
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[[Category: Anderson, W F.]]
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[[Category: Anderson, W F]]
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Structural genomic]]
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[[Category: Grimshaw, S.]]
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[[Category: Grimshaw, S]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak, A]]
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[[Category: Osipiuk, J.]]
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[[Category: Osipiuk, J]]
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[[Category: Zhou, M.]]
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[[Category: Zhou, M]]
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[[Category: Center for structural genomics of infectious disease]]
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[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Idp02355]]
[[Category: Idp02355]]
[[Category: Lipopolysaccharide biosynthesis]]
[[Category: Lipopolysaccharide biosynthesis]]
[[Category: Nucleotidyltransferase]]
[[Category: Nucleotidyltransferase]]
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[[Category: Structural genomic]]
 
[[Category: Transferase]]
[[Category: Transferase]]

Current revision

3-deoxy-manno-octulosonate cytidylyltransferase from Yersinia pestis

3jtj, resolution 2.18Å

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