3v62

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{{STRUCTURE_3v62| PDB=3v62 | SCENE= }}
 
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===Structure of the S. cerevisiae Srs2 C-terminal domain in complex with PCNA conjugated to SUMO on lysine 164===
 
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{{ABSTRACT_PUBMED_22382979}}
 
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==Function==
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==Structure of the S. cerevisiae Srs2 C-terminal domain in complex with PCNA conjugated to SUMO on lysine 164==
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[[http://www.uniprot.org/uniprot/SMT3_YEAST SMT3_YEAST]] Not known; suppressor of MIF2 mutations. [[http://www.uniprot.org/uniprot/SRS2_YEAST SRS2_YEAST]] ATP-dependent DNA helicase involved in DNA repair at least for UV-induced lesions. The polarity of the helicase activity was determined to be 3' to 5'. [[http://www.uniprot.org/uniprot/PCNA_YEAST PCNA_YEAST]] This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Involved in DNA repair.<ref>PMID:11545742</ref> <ref>PMID:12226657</ref>
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<StructureSection load='3v62' size='340' side='right'caption='[[3v62]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[3v62]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V62 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V62 FirstGlance]. <br>
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[[3v62]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V62 OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=NEQ:N-ETHYLMALEIMIDE'>NEQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v62 OCA], [https://pdbe.org/3v62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v62 RCSB], [https://www.ebi.ac.uk/pdbsum/3v62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v62 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SMT3_YEAST SMT3_YEAST] Not known; suppressor of MIF2 mutations.
==See Also==
==See Also==
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*[[Proliferating Cell Nuclear Antigen|Proliferating Cell Nuclear Antigen]]
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*[[Proliferating cell nuclear antigen 3D structures|Proliferating cell nuclear antigen 3D structures]]
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*[[SUMO|SUMO]]
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*[[SUMO 3D Structures|SUMO 3D Structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<references group="xtra"/><references/>
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[[Category: Large Structures]]
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[[Category: DNA helicase]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Saccharomyces cerevisiae s288c]]
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[[Category: Armstrong AA]]
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[[Category: Armstrong, A A.]]
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[[Category: Lima CD]]
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[[Category: Lima, C D.]]
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[[Category: Mohideen F]]
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[[Category: Mohideen, F.]]
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[[Category: Nem modification on pcna cys22 and cys81 reductive methylation of all lysine residues on smt3]]
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[[Category: Nuclear]]
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[[Category: Post-translational modification dna replication dna damage response]]
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[[Category: Protein binding-dna binding protein complex]]
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[[Category: Srs2]]
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[[Category: Ubiquitin-like protein pcna]]
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Current revision

Structure of the S. cerevisiae Srs2 C-terminal domain in complex with PCNA conjugated to SUMO on lysine 164

PDB ID 3v62

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