3w73

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'''Unreleased structure'''
 
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The entry 3w73 is ON HOLD until Paper Publication
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==Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-4-129==
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<StructureSection load='3w73' size='340' side='right'caption='[[3w73]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3w73]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi_strain_CL_Brener Trypanosoma cruzi strain CL Brener]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W73 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W73 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=W73:2,6-DIOXO-5-[2-(PHENANTHREN-9-YL)ETHYL]-1,2,3,6-+TETRAHYDROPYRIMIDINE-4-CARBOXYLIC+ACID'>W73</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w73 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w73 OCA], [https://pdbe.org/3w73 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w73 RCSB], [https://www.ebi.ac.uk/pdbsum/3w73 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w73 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro.
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Authors: Inaoka, D.K., Iida, M., Tabuchi, T., Lee, N., Hashimoto, S., Matsuoka, S., Kuranaga, T., Shiba, T., Sakamoto, K., Suzuki, S., Balogun, E.O., Nara, T., Aoki, T., Inoue, M., Honma, T., Tanaka, A., Harada, S., Kita, K.
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==See Also==
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*[[Dihydroorotate dehydrogenase 3D structures|Dihydroorotate dehydrogenase 3D structures]]
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Description: Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-4-129
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Trypanosoma cruzi strain CL Brener]]
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[[Category: Aoki T]]
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[[Category: Balogun EO]]
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[[Category: Harada S]]
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[[Category: Hashimoto S]]
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[[Category: Honma T]]
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[[Category: Iida M]]
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[[Category: Inaoka DK]]
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[[Category: Inoue M]]
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[[Category: Kita K]]
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[[Category: Kuranaga T]]
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[[Category: Lee N]]
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[[Category: Matsuoka S]]
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[[Category: Nara T]]
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[[Category: Sakamoto K]]
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[[Category: Shiba T]]
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[[Category: Suzuki S]]
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[[Category: Tabuchi T]]
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[[Category: Tanaka A]]

Current revision

Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-4-129

PDB ID 3w73

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OCA

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