2dto

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[[Image:2dto.jpg|left|200px]]<br /><applet load="2dto" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2dto, resolution 1.50&Aring;" />
 
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'''Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii OT3 Complexed with ATP and Biotin'''<br />
 
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==About this Structure==
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==Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii OT3 Complexed with ATP and Biotin==
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2DTO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii] with <scene name='pdbligand=ATP:'>ATP</scene> and <scene name='pdbligand=BTN:'>BTN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Biotin--[acetyl-CoA-carboxylase]_ligase Biotin--[acetyl-CoA-carboxylase] ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.15 6.3.4.15] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DTO OCA].
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<StructureSection load='2dto' size='340' side='right'caption='[[2dto]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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[[Category: Biotin--[acetyl-CoA-carboxylase] ligase]]
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== Structural highlights ==
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[[Category: Pyrococcus horikoshii]]
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<table><tr><td colspan='2'>[[2dto]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DTO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DTO FirstGlance]. <br>
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[[Category: Single protein]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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[[Category: Bagautdinov, B.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=BTN:BIOTIN'>BTN</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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[[Category: Kunishima, N.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dto FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dto OCA], [https://pdbe.org/2dto PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dto RCSB], [https://www.ebi.ac.uk/pdbsum/2dto PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dto ProSAT], [https://www.topsan.org/Proteins/RSGI/2dto TOPSAN]</span></td></tr>
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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</table>
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[[Category: ATP]]
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== Function ==
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[[Category: BTN]]
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[https://www.uniprot.org/uniprot/O57883_PYRHO O57883_PYRHO]
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[[Category: biotin biosynthesis]]
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== Evolutionary Conservation ==
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[[Category: dimer]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: national project on protein structural and functional analyses]]
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Check<jmol>
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[[Category: nppsfa]]
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<jmolCheckbox>
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[[Category: riken structural genomics/proteomics initiative]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dt/2dto_consurf.spt"</scriptWhenChecked>
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[[Category: rsgi]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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[[Category: structural genomics]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: x-ray diffraction]]
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dto ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:02:28 2008''
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==See Also==
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*[[Biotin Protein Ligase 3D structures|Biotin Protein Ligase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Pyrococcus horikoshii OT3]]
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[[Category: Bagautdinov B]]
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[[Category: Kunishima N]]

Current revision

Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii OT3 Complexed with ATP and Biotin

PDB ID 2dto

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