4j1w
From Proteopedia
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| - | {{STRUCTURE_4j1w| PDB=4j1w | SCENE= }} | ||
| - | ===Crystal Structure of Fe(II)-HppE with alternative substrate (R)-1-HPP=== | ||
| - | == | + | ==Crystal Structure of Fe(II)-HppE with alternative substrate (R)-1-HPP== |
| - | [[4j1w]] is a 3 chain structure with sequence from [ | + | <StructureSection load='4j1w' size='340' side='right'caption='[[4j1w]], [[Resolution|resolution]] 2.72Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4j1w]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_wedmorensis Streptomyces wedmorensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J1W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J1W FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.72Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=FFQ:[(1R)-1-HYDROXYPROPYL]PHOSPHONIC+ACID'>FFQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j1w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j1w OCA], [https://pdbe.org/4j1w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j1w RCSB], [https://www.ebi.ac.uk/pdbsum/4j1w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j1w ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HPPE_STRWE HPPE_STRWE] Non-heme-dependent dioxygenase that catalyzes the oxidative epoxidation of (S)-2-hydroxypropylphosphonate into (1R,2S)-epoxypropylphosphonate, the final step in the biosynthesis of fosfomycin antibiotic.<ref>PMID:16015285</ref> <ref>PMID:16186494</ref> | ||
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| + | ==See Also== | ||
| + | *[[Epoxidase 3D structures|Epoxidase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Streptomyces wedmorensis]] | [[Category: Streptomyces wedmorensis]] | ||
| - | [[Category: Dey | + | [[Category: Dey M]] |
| - | [[Category: Drennan | + | [[Category: Drennan CL]] |
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Current revision
Crystal Structure of Fe(II)-HppE with alternative substrate (R)-1-HPP
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