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3kg1

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{{STRUCTURE_3kg1| PDB=3kg1 | SCENE= }}
 
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===Crystal structure of SnoaB, a cofactor-independent oxygenase from Streptomyces nogalater, mutant N63A===
 
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{{ABSTRACT_PUBMED_20052967}}
 
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==About this Structure==
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==Crystal structure of SnoaB, a cofactor-independent oxygenase from Streptomyces nogalater, mutant N63A==
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[[3kg1]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_nogalater Streptomyces nogalater]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KG1 OCA].
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<StructureSection load='3kg1' size='340' side='right'caption='[[3kg1]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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== Structural highlights ==
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==Reference==
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<table><tr><td colspan='2'>[[3kg1]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_nogalater Streptomyces nogalater]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KG1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KG1 FirstGlance]. <br>
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<ref group="xtra">PMID:020052967</ref><ref group="xtra">PMID:019255477</ref><references group="xtra"/><references/>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kg1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kg1 OCA], [https://pdbe.org/3kg1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kg1 RCSB], [https://www.ebi.ac.uk/pdbsum/3kg1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kg1 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SNOAB_STRNO SNOAB_STRNO] Involved in the biosynthesis of the anthracycline (aromatic polyketide) antibiotic nogalamycin (PubMed:8760909, PubMed:8668120). Catalyzes the oxygenation of 12-deoxy-nogalonic acid at position 12 to yield nogalonic acid (PubMed:19255477, PubMed:20052967).<ref>PMID:8668120</ref> <ref>PMID:8760909</ref> <ref>PMID:19255477</ref> <ref>PMID:20052967</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kg/3kg1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kg1 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Streptomyces nogalater]]
[[Category: Streptomyces nogalater]]
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[[Category: Grocholski, T.]]
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[[Category: Grocholski T]]
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[[Category: Koskiniemi, H.]]
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[[Category: Koskiniemi H]]
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[[Category: Lindqvist, Y.]]
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[[Category: Lindqvist Y]]
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[[Category: Mantsala, P.]]
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[[Category: Mantsala P]]
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[[Category: Niemi, J.]]
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[[Category: Niemi J]]
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[[Category: Schneider, G.]]
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[[Category: Schneider G]]
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[[Category: Anthracycline]]
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[[Category: Cofactor-independent]]
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[[Category: Oxidoreductase]]
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[[Category: Oxygenase]]
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[[Category: Polyketide]]
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Current revision

Crystal structure of SnoaB, a cofactor-independent oxygenase from Streptomyces nogalater, mutant N63A

PDB ID 3kg1

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