3k6l
From Proteopedia
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| - | {{STRUCTURE_3k6l| PDB=3k6l | SCENE= }} | ||
| - | ===The structure of E.coli peptide deformylase (PDF) in complex with peptidomimetic ligand BB2827=== | ||
| - | == | + | ==The structure of E.coli peptide deformylase (PDF) in complex with peptidomimetic ligand BB2827== |
| - | [[http://www.uniprot.org/uniprot/DEF_ECOLI DEF_ECOLI | + | <StructureSection load='3k6l' size='340' side='right'caption='[[3k6l]], [[Resolution|resolution]] 2.15Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[3k6l]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K6L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3K6L FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> |
| - | [[Category: Escherichia coli | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2BB:(2S,3R)-N~4~-[(1S)-1-(DIMETHYLCARBAMOYL)-2,2-DIMETHYLPROPYL]-N~1~,2-DIHYDROXY-3-(2-METHYLPROPYL)BUTANEDIAMIDE'>2BB</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3k6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k6l OCA], [https://pdbe.org/3k6l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3k6l RCSB], [https://www.ebi.ac.uk/pdbsum/3k6l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3k6l ProSAT]</span></td></tr> |
| - | [[Category: Barker | + | </table> |
| - | [[Category: Cheng | + | == Function == |
| - | [[Category: Crawley | + | [https://www.uniprot.org/uniprot/DEF_ECOLI DEF_ECOLI] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163] |
| - | [[Category: Felicetti | + | == Evolutionary Conservation == |
| - | [[Category: Whittaker | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[Category: Wood | + | Check<jmol> |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k6/3k6l_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | + | </jmolCheckbox> | |
| - | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3k6l ConSurf]. | |
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Barker J]] | ||
| + | [[Category: Cheng RKY]] | ||
| + | [[Category: Crawley L]] | ||
| + | [[Category: Felicetti B]] | ||
| + | [[Category: Whittaker M]] | ||
| + | [[Category: Wood M]] | ||
Current revision
The structure of E.coli peptide deformylase (PDF) in complex with peptidomimetic ligand BB2827
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