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3kwu

From Proteopedia

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{{STRUCTURE_3kwu| PDB=3kwu | SCENE= }}
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#REDIRECT [[6nyt]] This PDB entry is obsolete and replaced by 6nyt
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===Munc13-1 C2B-domain, calcium bound===
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{{ABSTRACT_PUBMED_20154707}}
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==Function==
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[[http://www.uniprot.org/uniprot/UN13A_RAT UN13A_RAT]] Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. Also involved in secretory granule priming in insulin secretion.<ref>PMID:9697857</ref> <ref>PMID:11343654</ref> <ref>PMID:11792326</ref>
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==About this Structure==
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[[3kwu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KWU OCA].
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==Reference==
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<ref group="xtra">PMID:020154707</ref><references group="xtra"/><references/>
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[[Category: Rattus norvegicus]]
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[[Category: Lu, J.]]
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[[Category: Machius, M.]]
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[[Category: Rizo, J.]]
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[[Category: Tomchick, D R.]]
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[[Category: Calcium binding protein]]
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[[Category: Metal binding protein]]
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[[Category: Phospholipid binding protein]]
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Current revision

  1. REDIRECT 6nyt This PDB entry is obsolete and replaced by 6nyt

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