3l1e
From Proteopedia
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- | {{STRUCTURE_3l1e| PDB=3l1e | SCENE= }} | ||
- | ===Bovine AlphaA crystallin Zinc Bound=== | ||
- | {{ABSTRACT_PUBMED_20440841}} | ||
- | == | + | ==Bovine AlphaA crystallin Zinc Bound== |
- | [[http://www.uniprot.org/uniprot/CRYAA_BOVIN CRYAA_BOVIN | + | <StructureSection load='3l1e' size='340' side='right'caption='[[3l1e]], [[Resolution|resolution]] 1.15Å' scene=''> |
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[3l1e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The July 2010 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Crystallins'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2010_7 10.2210/rcsb_pdb/mom_2010_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L1E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L1E FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.15Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l1e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l1e OCA], [https://pdbe.org/3l1e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l1e RCSB], [https://www.ebi.ac.uk/pdbsum/3l1e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l1e ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/CRYAA_BOVIN CRYAA_BOVIN] May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l1/3l1e_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3l1e ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
- | == | + | ==See Also== |
- | [[ | + | *[[Crystallin 3D structures|Crystallin 3D structures]] |
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | + | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Crystallins]] | [[Category: Crystallins]] | ||
+ | [[Category: Large Structures]] | ||
[[Category: RCSB PDB Molecule of the Month]] | [[Category: RCSB PDB Molecule of the Month]] | ||
- | [[Category: Cascio | + | [[Category: Cascio D]] |
- | [[Category: Eisenberg | + | [[Category: Eisenberg D]] |
- | [[Category: Laganowsky | + | [[Category: Laganowsky A]] |
- | [[Category: Sawaya | + | [[Category: Sawaya MR]] |
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Current revision
Bovine AlphaA crystallin Zinc Bound
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