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3ljr
From Proteopedia
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| - | {{STRUCTURE_3ljr| PDB=3ljr | SCENE= }} | ||
| - | ===GLUTATHIONE TRANSFERASE (THETA CLASS) FROM HUMAN IN COMPLEX WITH THE GLUTATHIONE CONJUGATE OF 1-MENAPHTHYL SULFATE=== | ||
| - | {{ABSTRACT_PUBMED_9551553}} | ||
| - | == | + | ==GLUTATHIONE TRANSFERASE (THETA CLASS) FROM HUMAN IN COMPLEX WITH THE GLUTATHIONE CONJUGATE OF 1-MENAPHTHYL SULFATE== |
| - | [[3ljr]] is a 2 chain structure with sequence from [ | + | <StructureSection load='3ljr' size='340' side='right'caption='[[3ljr]], [[Resolution|resolution]] 3.30Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3ljr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LJR FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GGC:1-MENAPHTHYL+GLUTATHIONE+CONJUGATE'>GGC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ljr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ljr OCA], [https://pdbe.org/3ljr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ljr RCSB], [https://www.ebi.ac.uk/pdbsum/3ljr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ljr ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GSTT2_HUMAN GSTT2_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lj/3ljr_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ljr ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Glutathione S-transferase|Glutathione S-transferase]] | + | *[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | + | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Board | + | [[Category: Large Structures]] |
| - | [[Category: Chelvanayagam | + | [[Category: Board PG]] |
| - | [[Category: Flanagan | + | [[Category: Chelvanayagam G]] |
| - | [[Category: Mckinstry | + | [[Category: Flanagan J]] |
| - | [[Category: Oakley | + | [[Category: Mckinstry WJ]] |
| - | [[Category: Parker | + | [[Category: Oakley AJ]] |
| - | [[Category: Rossjohn | + | [[Category: Parker MW]] |
| - | [[Category: Tan | + | [[Category: Rossjohn J]] |
| - | [[Category: Verger | + | [[Category: Tan KL]] |
| - | + | [[Category: Verger D]] | |
Current revision
GLUTATHIONE TRANSFERASE (THETA CLASS) FROM HUMAN IN COMPLEX WITH THE GLUTATHIONE CONJUGATE OF 1-MENAPHTHYL SULFATE
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Categories: Homo sapiens | Large Structures | Board PG | Chelvanayagam G | Flanagan J | Mckinstry WJ | Oakley AJ | Parker MW | Rossjohn J | Tan KL | Verger D
