2e72
From Proteopedia
(Difference between revisions)
| (15 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2e72.jpg|left|200px]]<br /><applet load="2e72" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2e72" /> | ||
| - | '''Solution structure of the zinc finger domain of human KIAA0461'''<br /> | ||
| - | == | + | ==Solution structure of the zinc finger domain of human KIAA0461== |
| - | + | <StructureSection load='2e72' size='340' side='right'caption='[[2e72]]' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2e72]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E72 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E72 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e72 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e72 OCA], [https://pdbe.org/2e72 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e72 RCSB], [https://www.ebi.ac.uk/pdbsum/2e72 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e72 ProSAT], [https://www.topsan.org/Proteins/RSGI/2e72 TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/POGZ_HUMAN POGZ_HUMAN] Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms.<ref>PMID:20562864</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Inoue | + | [[Category: Inoue M]] |
| - | [[Category: Kigawa | + | [[Category: Kigawa T]] |
| - | [[Category: Muto | + | [[Category: Muto Y]] |
| - | + | [[Category: Shirouzu M]] | |
| - | [[Category: Shirouzu | + | [[Category: Suzuki S]] |
| - | [[Category: Suzuki | + | [[Category: Tanabe W]] |
| - | [[Category: Tanabe | + | [[Category: Terada T]] |
| - | [[Category: Terada | + | [[Category: Yokoyama S]] |
| - | [[Category: Yokoyama | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Solution structure of the zinc finger domain of human KIAA0461
| |||||||||||
Categories: Homo sapiens | Large Structures | Inoue M | Kigawa T | Muto Y | Shirouzu M | Suzuki S | Tanabe W | Terada T | Yokoyama S
