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3kyz
From Proteopedia
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| - | {{STRUCTURE_3kyz| PDB=3kyz | SCENE= }} | ||
| - | ===The crystal structure of the sensor domain of two-component sensor PfeS from Pseudomonas aeruginosa PA01=== | ||
| - | ==Function== | + | ==The crystal structure of the sensor domain of two-component sensor PfeS from Pseudomonas aeruginosa PA01== |
| + | <StructureSection load='3kyz' size='340' side='right' caption='[[3kyz]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3kyz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KYZ FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr> | ||
| + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pfeS, PA2687 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kyz OCA], [http://pdbe.org/3kyz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kyz RCSB], [http://www.ebi.ac.uk/pdbsum/3kyz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kyz ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
[[http://www.uniprot.org/uniprot/PFES_PSEAE PFES_PSEAE]] Member of the two-component regulatory system PfeR/PfeS. May activate PfeR by phosphorylation. | [[http://www.uniprot.org/uniprot/PFES_PSEAE PFES_PSEAE]] Member of the two-component regulatory system PfeR/PfeS. May activate PfeR by phosphorylation. | ||
| - | + | == Evolutionary Conservation == | |
| - | == | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[ | + | Check<jmol> |
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ky/3kyz_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kyz ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Histidine kinase]] | [[Category: Histidine kinase]] | ||
| - | + | [[Category: Buck, K]] | |
| - | [[Category: Buck, K | + | [[Category: Joachimiak, A]] |
| - | [[Category: Joachimiak, A | + | [[Category: Structural genomic]] |
| - | [[Category: | + | [[Category: Marshall, N]] |
| - | [[Category: Marshall, N | + | [[Category: Tan, K]] |
| - | [[Category: Tan, K | + | |
[[Category: Apc37897 4]] | [[Category: Apc37897 4]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
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[[Category: Mcsg]] | [[Category: Mcsg]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
| - | [[Category: Midwest center for structural genomic]] | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Protein structure initiative]] | + | [[Category: PSI, Protein structure initiative]] |
[[Category: Pseudomonas aeruginosa pa01]] | [[Category: Pseudomonas aeruginosa pa01]] | ||
| - | [[Category: Psi-2]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: The sensor domain of two-component sensor pfe]] | [[Category: The sensor domain of two-component sensor pfe]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Two-component regulatory system]] | [[Category: Two-component regulatory system]] | ||
Current revision
The crystal structure of the sensor domain of two-component sensor PfeS from Pseudomonas aeruginosa PA01
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Categories: Histidine kinase | Buck, K | Joachimiak, A | Structural genomic | Marshall, N | Tan, K | Apc37897 4 | Atp-binding | Cell inner membrane | Cell membrane | Kinase | Mcsg | Membrane | Nucleotide-binding | Phosphoprotein | PSI, Protein structure initiative | Pseudomonas aeruginosa pa01 | The sensor domain of two-component sensor pfe | Transferase | Transmembrane | Two-component regulatory system
