3tsb

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{{STRUCTURE_3tsb| PDB=3tsb | SCENE= }}
 
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===Crystal Structure of Inosine-5'-monophosphate Dehydrogenase from Bacillus anthracis str. Ames===
 
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{{ABSTRACT_PUBMED_22788966}}
 
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==Function==
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==Crystal Structure of Inosine-5'-monophosphate Dehydrogenase from Bacillus anthracis str. Ames==
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[[http://www.uniprot.org/uniprot/Q81W29_BACAN Q81W29_BACAN]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]
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<StructureSection load='3tsb' size='340' side='right'caption='[[3tsb]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3tsb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._Ames Bacillus anthracis str. Ames]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TSB FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.595&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tsb OCA], [https://pdbe.org/3tsb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tsb RCSB], [https://www.ebi.ac.uk/pdbsum/3tsb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tsb ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A6L8P2U9_BACAN A0A6L8P2U9_BACAN] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964]
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==About this Structure==
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==See Also==
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[[3tsb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis_str._ames Bacillus anthracis str. ames]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSB OCA].
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*[[Inosine monophosphate dehydrogenase 3D structures|Inosine monophosphate dehydrogenase 3D structures]]
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[[Category: Bacillus anthracis str. ames]]
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__TOC__
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[[Category: IMP dehydrogenase]]
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</StructureSection>
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Bacillus anthracis str. Ames]]
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[[Category: Hasseman, J.]]
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[[Category: Large Structures]]
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[[Category: Joachimiak, A.]]
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[[Category: Anderson WF]]
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[[Category: Kim, Y.]]
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[[Category: Hasseman J]]
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[[Category: Makowska-Grzyska, M.]]
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[[Category: Joachimiak A]]
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[[Category: Cbs-domain]]
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[[Category: Kim Y]]
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[[Category: Center for structural genomics of infectious disease]]
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[[Category: Makowska-Grzyska M]]
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[[Category: Csgid]]
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[[Category: Cytosol]]
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[[Category: Oxidoreductase]]
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[[Category: Structural genomic]]
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[[Category: Tim-barrel]]
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Current revision

Crystal Structure of Inosine-5'-monophosphate Dehydrogenase from Bacillus anthracis str. Ames

PDB ID 3tsb

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