4j2w
From Proteopedia
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- | {{STRUCTURE_4j2w| PDB=4j2w | SCENE= }} | ||
- | ===Crystal Structure of kynurenine 3-monooxygenase (KMO-396Prot-Se)=== | ||
- | == | + | ==Crystal Structure of kynurenine 3-monooxygenase (KMO-396Prot-Se)== |
- | [[http://www.uniprot.org/uniprot/KMO_YEAST KMO_YEAST | + | <StructureSection load='4j2w' size='340' side='right'caption='[[4j2w]], [[Resolution|resolution]] 2.60Å' scene=''> |
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[4j2w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J2W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J2W FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j2w OCA], [https://pdbe.org/4j2w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j2w RCSB], [https://www.ebi.ac.uk/pdbsum/4j2w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j2w ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/KMO_YEAST KMO_YEAST] Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.<ref>PMID:12062417</ref> <ref>PMID:15806102</ref> | ||
- | == | + | ==See Also== |
- | [[ | + | *[[Monooxygenase 3D structures|Monooxygenase 3D structures]] |
- | + | == References == | |
- | == | + | <references/> |
- | <references | + | __TOC__ |
- | [[Category: | + | </StructureSection> |
- | [[Category: Saccharomyces cerevisiae | + | [[Category: Large Structures]] |
- | [[Category: Amaral | + | [[Category: Saccharomyces cerevisiae S288C]] |
- | [[Category: Giorgini | + | [[Category: Amaral M]] |
- | [[Category: Heyes | + | [[Category: Giorgini F]] |
- | [[Category: Lafite | + | [[Category: Heyes DJ]] |
- | [[Category: Levy | + | [[Category: Lafite P]] |
- | [[Category: Leys | + | [[Category: Levy C]] |
- | [[Category: Outeiro | + | [[Category: Leys D]] |
- | [[Category: Scrutton | + | [[Category: Outeiro TF]] |
- | + | [[Category: Scrutton NS]] | |
- | + |
Current revision
Crystal Structure of kynurenine 3-monooxygenase (KMO-396Prot-Se)
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