4j2w

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{{STRUCTURE_4j2w| PDB=4j2w | SCENE= }}
 
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===Crystal Structure of kynurenine 3-monooxygenase (KMO-396Prot-Se)===
 
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==Function==
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==Crystal Structure of kynurenine 3-monooxygenase (KMO-396Prot-Se)==
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[[http://www.uniprot.org/uniprot/KMO_YEAST KMO_YEAST]] Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.<ref>PMID:12062417</ref> <ref>PMID:15806102</ref>
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<StructureSection load='4j2w' size='340' side='right'caption='[[4j2w]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4j2w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J2W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J2W FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j2w OCA], [https://pdbe.org/4j2w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j2w RCSB], [https://www.ebi.ac.uk/pdbsum/4j2w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j2w ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KMO_YEAST KMO_YEAST] Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.<ref>PMID:12062417</ref> <ref>PMID:15806102</ref>
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==About this Structure==
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==See Also==
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[[4j2w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J2W OCA].
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*[[Monooxygenase 3D structures|Monooxygenase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<references group="xtra"/><references/>
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__TOC__
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[[Category: Kynurenine 3-monooxygenase]]
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</StructureSection>
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[[Category: Saccharomyces cerevisiae s288c]]
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[[Category: Large Structures]]
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[[Category: Amaral, M.]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Giorgini, F.]]
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[[Category: Amaral M]]
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[[Category: Heyes, D J.]]
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[[Category: Giorgini F]]
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[[Category: Lafite, P.]]
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[[Category: Heyes DJ]]
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[[Category: Levy, C.]]
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[[Category: Lafite P]]
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[[Category: Leys, D.]]
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[[Category: Levy C]]
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[[Category: Outeiro, T F.]]
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[[Category: Leys D]]
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[[Category: Scrutton, N S.]]
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[[Category: Outeiro TF]]
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[[Category: Monooxygenase]]
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[[Category: Scrutton NS]]
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[[Category: Oxidoreductase]]
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Current revision

Crystal Structure of kynurenine 3-monooxygenase (KMO-396Prot-Se)

PDB ID 4j2w

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