2ebt

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="2ebt" size="350" color="white" frame="true" align="right" spinBox="true" caption="2ebt" /> '''Solution structure of three tandem repeats o...)
Current revision (18:48, 29 May 2024) (edit) (undo)
 
(18 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2ebt.jpg|left|200px]]<br /><applet load="2ebt" size="350" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2ebt" />
 
-
'''Solution structure of three tandem repeats of zf-C2H2 domains from human Kruppel-like factor 5'''<br />
 
-
==About this Structure==
+
==Solution structure of three tandem repeats of zf-C2H2 domains from human Kruppel-like factor 5==
-
2EBT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Sites: <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+100'>AC1</scene>, <scene name='pdbsite=AC2:Zn+Binding+Site+For+Residue+A+200'>AC2</scene> and <scene name='pdbsite=AC3:Zn+Binding+Site+For+Residue+A+300'>AC3</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBT OCA].
+
<StructureSection load='2ebt' size='340' side='right'caption='[[2ebt]]' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2ebt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The April 2009 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Oct and Sox Transcription Factors'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2009_4 10.2210/rcsb_pdb/mom_2009_4]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EBT FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ebt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ebt OCA], [https://pdbe.org/2ebt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ebt RCSB], [https://www.ebi.ac.uk/pdbsum/2ebt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ebt ProSAT], [https://www.topsan.org/Proteins/RSGI/2ebt TOPSAN]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/KLF5_HUMAN KLF5_HUMAN] Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/2ebt_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ebt ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Hayashi, F.]]
+
[[Category: Oct and Sox Transcription Factors]]
-
[[Category: Nagashima, T.]]
+
[[Category: RCSB PDB Molecule of the Month]]
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
[[Category: Hayashi F]]
-
[[Category: Yokoyama, S.]]
+
[[Category: Nagashima T]]
-
[[Category: ZN]]
+
[[Category: Yokoyama S]]
-
[[Category: c2h2-type zinc-finger]]
+
-
[[Category: gc-box promoter elements]]
+
-
[[Category: kruppel-like factor]]
+
-
[[Category: metal bind]]
+
-
[[Category: national project on protein structural and functional analyses]]
+
-
[[Category: nppsfa]]
+
-
[[Category: riken structural genomics/proteomics initiative]]
+
-
[[Category: rsgi]]
+
-
[[Category: structural genomics]]
+
-
[[Category: transcription factor]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:08:32 2008''
+

Current revision

Solution structure of three tandem repeats of zf-C2H2 domains from human Kruppel-like factor 5

PDB ID 2ebt

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2ebt"
Personal tools