This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3m70
From Proteopedia
(Difference between revisions)
m (Protected "3m70" [edit=sysop:move=sysop]) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_3m70| PDB=3m70 | SCENE= }} | ||
| - | ===Crystal Structure of TehB from Haemophilus influenzae=== | ||
| - | ==Function== | + | ==Crystal Structure of TehB from Haemophilus influenzae== |
| + | <StructureSection load='3m70' size='340' side='right' caption='[[3m70]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3m70]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_influenzae"_lehmann_and_neumann_1896 "bacterium influenzae" lehmann and neumann 1896]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M70 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3M70 FirstGlance]. <br> | ||
| + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HI1275, Rd, tehB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 "Bacterium influenzae" Lehmann and Neumann 1896])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3m70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m70 OCA], [http://pdbe.org/3m70 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3m70 RCSB], [http://www.ebi.ac.uk/pdbsum/3m70 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3m70 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
[[http://www.uniprot.org/uniprot/TEHB_HAEIN TEHB_HAEIN]] Probable S-adenosyl-L-methionine-dependent methyltransferase. Plays a role in both resistance to oxidative damage and heme uptake/utilization. Also protects H.influenzae from tellurite exposure in vitro; however, since H.influenzae grows only in humans, it is unlikely to encounter tellurite in its natural environment, and it is thus probable that tellurite resistance does not represent a biologically relevant role of TehB (By similarity). | [[http://www.uniprot.org/uniprot/TEHB_HAEIN TEHB_HAEIN]] Probable S-adenosyl-L-methionine-dependent methyltransferase. Plays a role in both resistance to oxidative damage and heme uptake/utilization. Also protects H.influenzae from tellurite exposure in vitro; however, since H.influenzae grows only in humans, it is unlikely to encounter tellurite in its natural environment, and it is thus probable that tellurite resistance does not represent a biologically relevant role of TehB (By similarity). | ||
| - | + | == Evolutionary Conservation == | |
| - | == | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[ | + | Check<jmol> |
| - | [[Category: | + | <jmolCheckbox> |
| - | [[Category: Chen, Y H | + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m7/3m70_consurf.spt"</scriptWhenChecked> |
| - | [[Category: Hendrickson, W A | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[Category: NYCOMPS, New York Consortium on Membrane Protein Structure | + | <text>to colour the structure by Evolutionary Conservation</text> |
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3m70 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bacterium influenzae lehmann and neumann 1896]] | ||
| + | [[Category: Chen, Y H]] | ||
| + | [[Category: Hendrickson, W A]] | ||
| + | [[Category: NYCOMPS, New York Consortium on Membrane Protein Structure]] | ||
[[Category: Cytoplasm]] | [[Category: Cytoplasm]] | ||
[[Category: New york consortium on membrane protein structure]] | [[Category: New york consortium on membrane protein structure]] | ||
[[Category: Nycomp]] | [[Category: Nycomp]] | ||
| - | [[Category: Protein structure initiative | + | [[Category: PSI, Protein structure initiative]] |
| - | + | ||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
[[Category: Tellurite resistance]] | [[Category: Tellurite resistance]] | ||
[[Category: Unknown function]] | [[Category: Unknown function]] | ||
Current revision
Crystal Structure of TehB from Haemophilus influenzae
| |||||||||||
Categories: Bacterium influenzae lehmann and neumann 1896 | Chen, Y H | Hendrickson, W A | NYCOMPS, New York Consortium on Membrane Protein Structure | Cytoplasm | New york consortium on membrane protein structure | Nycomp | PSI, Protein structure initiative | Structural genomic | Tellurite resistance | Unknown function

