2eeo

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(New page: 200px<br /><applet load="2eeo" size="350" color="white" frame="true" align="right" spinBox="true" caption="2eeo, resolution 1.60&Aring;" /> '''Crystal Structure of...)
Current revision (08:38, 25 October 2023) (edit) (undo)
 
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[[Image:2eeo.jpg|left|200px]]<br /><applet load="2eeo" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2eeo, resolution 1.60&Aring;" />
 
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'''Crystal Structure of T.th. HB8 L-Aspartate-alpha-Decarboxylase Complexed with Fumarate'''<br />
 
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==About this Structure==
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==Crystal Structure of T.th. HB8 L-Aspartate-alpha-Decarboxylase Complexed with Fumarate==
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2EEO is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=PYR:'>PYR</scene> and <scene name='pdbligand=FMR:'>FMR</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Aspartate_1-decarboxylase Aspartate 1-decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.11 4.1.1.11] Known structural/functional Sites: <scene name='pdbsite=AC1:Pyr+Binding+Site+For+Residue+B+25'>AC1</scene> and <scene name='pdbsite=AC2:Fmr+Binding+Site+For+Residue+B+501'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EEO OCA].
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<StructureSection load='2eeo' size='340' side='right'caption='[[2eeo]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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[[Category: Aspartate 1-decarboxylase]]
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== Structural highlights ==
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[[Category: Protein complex]]
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<table><tr><td colspan='2'>[[2eeo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EEO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EEO FirstGlance]. <br>
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[[Category: Thermus thermophilus]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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[[Category: Goto, M.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUM:FUMARIC+ACID'>FUM</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
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[[Category: FMR]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eeo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eeo OCA], [https://pdbe.org/2eeo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eeo RCSB], [https://www.ebi.ac.uk/pdbsum/2eeo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eeo ProSAT], [https://www.topsan.org/Proteins/RSGI/2eeo TOPSAN]</span></td></tr>
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[[Category: PYR]]
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</table>
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[[Category: lyase]]
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== Function ==
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[[Category: pyruvoyl group dependent enzyme]]
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[https://www.uniprot.org/uniprot/PAND_THET8 PAND_THET8] Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ee/2eeo_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eeo ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:09:19 2008''
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==See Also==
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*[[Aspartate decarboxylase 3D structures|Aspartate decarboxylase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Goto M]]

Current revision

Crystal Structure of T.th. HB8 L-Aspartate-alpha-Decarboxylase Complexed with Fumarate

PDB ID 2eeo

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