2egw
From Proteopedia
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| - | [[Image:2egw.jpg|left|200px]]<br /><applet load="2egw" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2egw, resolution 2.80Å" /> | ||
| - | '''Crystal structure of rRNA methyltransferase with SAH ligand'''<br /> | ||
| - | == | + | ==Crystal structure of rRNA methyltransferase with SAH ligand== |
| - | + | <StructureSection load='2egw' size='340' side='right'caption='[[2egw]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2egw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EGW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EGW FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2egw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2egw OCA], [https://pdbe.org/2egw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2egw RCSB], [https://www.ebi.ac.uk/pdbsum/2egw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2egw ProSAT], [https://www.topsan.org/Proteins/RSGI/2egw TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RSME_AQUAE RSME_AQUAE] Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eg/2egw_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2egw ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Aquifex aeolicus]] | [[Category: Aquifex aeolicus]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Bessho | + | [[Category: Bessho Y]] |
| - | [[Category: Dong | + | [[Category: Dong X]] |
| - | + | [[Category: Shirouzu M]] | |
| - | [[Category: Shirouzu | + | [[Category: Yokoyama S]] |
| - | [[Category: Yokoyama | + | |
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Current revision
Crystal structure of rRNA methyltransferase with SAH ligand
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