4ik0

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{{STRUCTURE_4ik0| PDB=4ik0 | SCENE= }}
 
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===Crystal structure of diaminopimelate epimerase Y268A mutant from Escherichia coli===
 
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{{ABSTRACT_PUBMED_23426375}}
 
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==Function==
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==Crystal structure of diaminopimelate epimerase Y268A mutant from Escherichia coli==
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[[http://www.uniprot.org/uniprot/DAPF_ECOLI DAPF_ECOLI]] Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan. Only accepts DAP isomers with the L configuration.<ref>PMID:6378903</ref> <ref>PMID:3031013</ref> <ref>PMID:3042781</ref>
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<StructureSection load='4ik0' size='340' side='right'caption='[[4ik0]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4ik0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IK0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IK0 FirstGlance]. <br>
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[[4ik0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IK0 OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ik0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ik0 OCA], [https://pdbe.org/4ik0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ik0 RCSB], [https://www.ebi.ac.uk/pdbsum/4ik0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ik0 ProSAT]</span></td></tr>
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<references group="xtra"/><references/>
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</table>
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[[Category: Diaminopimelate epimerase]]
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== Function ==
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[[Category: Escherichia coli k-12]]
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[https://www.uniprot.org/uniprot/DAPF_ECOLI DAPF_ECOLI] Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan. Only accepts DAP isomers with the L configuration.<ref>PMID:6378903</ref> <ref>PMID:3031013</ref> <ref>PMID:3042781</ref>
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[[Category: Dobson, R C.J.]]
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== References ==
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[[Category: Hor, L.]]
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<references/>
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[[Category: Hutton, C A.]]
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__TOC__
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[[Category: Perugini, M A.]]
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</StructureSection>
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[[Category: Cytosol]]
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[[Category: Escherichia coli K-12]]
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[[Category: Dap epimerase-like]]
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[[Category: Large Structures]]
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[[Category: Isomerase]]
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[[Category: Dobson RCJ]]
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[[Category: Hor L]]
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[[Category: Hutton CA]]
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[[Category: Perugini MA]]

Current revision

Crystal structure of diaminopimelate epimerase Y268A mutant from Escherichia coli

PDB ID 4ik0

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