4i6w
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==3-hydroxy-3-methylglutaryl (HMG) Coenzyme-A reductase complexed with thiomevalonate== | |
| + | <StructureSection load='4i6w' size='340' side='right'caption='[[4i6w]], [[Resolution|resolution]] 1.66Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4i6w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_mevalonii Pseudomonas mevalonii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I6W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I6W FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1CO:(3S)-3-HYDROXY-3-METHYL-5-SULFANYLPENTANOIC+ACID'>1CO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i6w OCA], [https://pdbe.org/4i6w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i6w RCSB], [https://www.ebi.ac.uk/pdbsum/4i6w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i6w ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MVAA_PSEMV MVAA_PSEMV] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA. | ||
| - | + | ==See Also== | |
| - | + | *[[HMG-CoA Reductase 3D structures|HMG-CoA Reductase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pseudomonas mevalonii]] | ||
| + | [[Category: Burgner II JW]] | ||
| + | [[Category: Critchelow CJ]] | ||
| + | [[Category: Min J]] | ||
| + | [[Category: Rodwell VW]] | ||
| + | [[Category: Schmidt T]] | ||
| + | [[Category: Stauffacher CV]] | ||
| + | [[Category: Steussy CN]] | ||
| + | [[Category: Wrensford LV]] | ||
Current revision
3-hydroxy-3-methylglutaryl (HMG) Coenzyme-A reductase complexed with thiomevalonate
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