4j5h

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'''Unreleased structure'''
 
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The entry 4j5h is ON HOLD until Paper Publication
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==Crystal Structure of B. thuringiensis AiiA mutant F107W with N-decanoyl-L-homoserine bound at the active site==
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<StructureSection load='4j5h' size='340' side='right'caption='[[4j5h]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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Authors: Liu, C.F., Liu, D., Momb, J., Thomas, P.W., Lajoie, A., Petsko, G.A., Fast, W., Ringe, D.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4j5h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thuringiensis Bacillus thuringiensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J5H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J5H FirstGlance]. <br>
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Description: Crystal Structure of B. thuringiensis AiiA mutant F107W with N-decanoyl-L-homoserine bound at the active site
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1K4:N-DECANOYL-L-HOMOSERINE'>1K4</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j5h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j5h OCA], [https://pdbe.org/4j5h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j5h RCSB], [https://www.ebi.ac.uk/pdbsum/4j5h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j5h ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AHLL_BACTU AHLL_BACTU] Catalyzes hydrolysis of N-hexanoyl-(S)-homoserine lactone, but not the R-enantiomer. Hydrolyzes short- and long-chain N-acyl homoserine lactones with or without 3-oxo substitution at C3, has maximum activity on C10-AHL.<ref>PMID:15895999</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Bacillus thuringiensis]]
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[[Category: Large Structures]]
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[[Category: Fast W]]
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[[Category: Lajoie A]]
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[[Category: Liu CF]]
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[[Category: Liu D]]
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[[Category: Momb J]]
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[[Category: Petsko GA]]
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[[Category: Ringe D]]
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[[Category: Thomas PW]]

Current revision

Crystal Structure of B. thuringiensis AiiA mutant F107W with N-decanoyl-L-homoserine bound at the active site

PDB ID 4j5h

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