2eo0
From Proteopedia
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| - | [[Image:2eo0.jpg|left|200px]]<br /><applet load="2eo0" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2eo0, resolution 2.4Å" /> | ||
| - | '''Crystal Structure of Holliday Junction Resolvase ST1444'''<br /> | ||
| - | == | + | ==Crystal Structure of Holliday Junction Resolvase ST1444== |
| - | + | <StructureSection load='2eo0' size='340' side='right'caption='[[2eo0]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | [ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[2eo0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii_str._7 Sulfurisphaera tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EO0 FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eo0 OCA], [https://pdbe.org/2eo0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eo0 RCSB], [https://www.ebi.ac.uk/pdbsum/2eo0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eo0 ProSAT], [https://www.topsan.org/Proteins/RSGI/2eo0 TOPSAN]</span></td></tr> |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/HJC_SULTO HJC_SULTO] A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products. Inhibits the helicase activity of Hel308 (Hjm).[HAMAP-Rule:MF_01490]<ref>PMID:18296528</ref> | |
| - | [[ | + | == Evolutionary Conservation == |
| - | [ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [ | + | Check<jmol> |
| - | [[ | + | <jmolCheckbox> |
| - | [ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/2eo0_consurf.spt"</scriptWhenChecked> |
| - | [[ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [ | + | <text>to colour the structure by Evolutionary Conservation</text> |
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eo0 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[Resolvase 3D structures|Resolvase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Sulfurisphaera tokodaii str. 7]] | ||
| + | [[Category: Kagawa W]] | ||
| + | [[Category: Kurumizaka H]] | ||
| + | [[Category: Sarai N]] | ||
| + | [[Category: Yokoyama S]] | ||
Current revision
Crystal Structure of Holliday Junction Resolvase ST1444
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