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4k1y
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Canavalia boliviana lectin in complex with Man1-3Man-OMe== | |
| - | + | <StructureSection load='4k1y' size='340' side='right'caption='[[4k1y]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4k1y]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_boliviana Canavalia boliviana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K1Y FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k1y OCA], [https://pdbe.org/4k1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k1y RCSB], [https://www.ebi.ac.uk/pdbsum/4k1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k1y ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LECA_CANBL LECA_CANBL] D-mannose/D-glucose-binding lectin (PubMed:24865454). Has anti-inflammatory activity in animal models when applied intravenously (PubMed:24865454). Has antinociceptive activity in mice when applied intravenously (PubMed:19705102).<ref>PMID:19705102</ref> <ref>PMID:24865454</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Canavalia boliviana]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bezerra GA]] | ||
| + | [[Category: Cavada BS]] | ||
| + | [[Category: Delatorre P]] | ||
| + | [[Category: Gruber K]] | ||
| + | [[Category: Moura TR]] | ||
| + | [[Category: Rocha BAM]] | ||
| + | [[Category: Viertlmayr R]] | ||
Current revision
Crystal structure of Canavalia boliviana lectin in complex with Man1-3Man-OMe
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