This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4k43
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4k43 is ON HOLD Authors: Pereira, J.H., Petchprayoon, C., Moriarty, N.W., Fink, S.J., Cecere, G., Paterson, I., Adams, P.D., Marriott, G. Descripti...) |
|||
| (11 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of actin in complex with synthetic AplC tail analogue GC04 [N-{(1E,4R,5R,7E,9S,10S,11S)-4,10-dimethoxy-11-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-5,9-dimethyl-6-oxododeca-1,7-dien-1-yl}-N-methylformamide]== | |
| + | <StructureSection load='4k43' size='340' side='right'caption='[[4k43]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4k43]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K43 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K43 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PO:N-{(1E,4R,5R,7E,9S,10S,11S)-4,10-DIMETHOXY-11-[(2S,4S,5S)-2-(4-METHOXYPHENYL)-5-METHYL-1,3-DIOXAN-4-YL]-5,9-DIMETHYL-6-OXODODECA-1,7-DIEN-1-YL}-N-METHYLFORMAMIDE'>1PO</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k43 OCA], [https://pdbe.org/4k43 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k43 RCSB], [https://www.ebi.ac.uk/pdbsum/4k43 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k43 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | ||
| - | + | ==See Also== | |
| - | + | *[[Actin 3D structures|Actin 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Oryctolagus cuniculus]] | ||
| + | [[Category: Adams PD]] | ||
| + | [[Category: Cecere G]] | ||
| + | [[Category: Fink SJ]] | ||
| + | [[Category: Marriott G]] | ||
| + | [[Category: Moriarty NW]] | ||
| + | [[Category: Paterson I]] | ||
| + | [[Category: Pereira JH]] | ||
| + | [[Category: Petchprayoon C]] | ||
Current revision
Crystal structure of actin in complex with synthetic AplC tail analogue GC04 [N-{(1E,4R,5R,7E,9S,10S,11S)-4,10-dimethoxy-11-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-5,9-dimethyl-6-oxododeca-1,7-dien-1-yl}-N-methylformamide]
| |||||||||||
