4jqo

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{{STRUCTURE_4jqo| PDB=4jqo | SCENE= }}
 
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===Crystal structure of anabolic ornithine carbamoyltransferase from Vibrio vulnificus in complex with citrulline and inorganic phosphate===
 
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==Function==
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==Crystal structure of anabolic ornithine carbamoyltransferase from Vibrio vulnificus in complex with citrulline and inorganic phosphate==
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[[http://www.uniprot.org/uniprot/OTC_VIBVU OTC_VIBVU]] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity).
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<StructureSection load='4jqo' size='340' side='right'caption='[[4jqo]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4jqo]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_vulnificus_CMCP6 Vibrio vulnificus CMCP6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JQO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JQO FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.082&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIR:CITRULLINE'>CIR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jqo OCA], [https://pdbe.org/4jqo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jqo RCSB], [https://www.ebi.ac.uk/pdbsum/4jqo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jqo ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/OTC_VIBVU OTC_VIBVU] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity).
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==About this Structure==
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==See Also==
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[[4jqo]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_vulnificus_cmcp6 Vibrio vulnificus cmcp6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JQO OCA].
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*[[Ornithine carbamoyltransferase 3D structures|Ornithine carbamoyltransferase 3D structures]]
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[[Category: Ornithine carbamoyltransferase]]
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__TOC__
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[[Category: Vibrio vulnificus cmcp6]]
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</StructureSection>
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[[Category: Anderson, W F.]]
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[[Category: Large Structures]]
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Vibrio vulnificus CMCP6]]
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[[Category: Domagalski, M J.]]
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[[Category: Anderson WF]]
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[[Category: Grimshaw, S.]]
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[[Category: Domagalski MJ]]
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[[Category: Minor, W.]]
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[[Category: Grimshaw S]]
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[[Category: Shabalin, I G.]]
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[[Category: Minor W]]
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[[Category: Winsor, J.]]
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[[Category: Shabalin IG]]
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[[Category: Carbamoyl phosphate]]
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[[Category: Winsor J]]
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[[Category: Center for structural genomics of infectious disease]]
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[[Category: Csgid]]
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[[Category: L-ornithine]]
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[[Category: National institute of allergy and infectious disease]]
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[[Category: Niaid]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]
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Current revision

Crystal structure of anabolic ornithine carbamoyltransferase from Vibrio vulnificus in complex with citrulline and inorganic phosphate

PDB ID 4jqo

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