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3n4p
From Proteopedia
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| - | {{STRUCTURE_3n4p| PDB=3n4p | SCENE= }} | ||
| - | ===Human cytomegalovirus terminase nuclease domain=== | ||
| - | {{ABSTRACT_PUBMED_20805464}} | ||
| - | == | + | ==Human cytomegalovirus terminase nuclease domain== |
| - | [[http://www.uniprot.org/uniprot/ | + | <StructureSection load='3n4p' size='340' side='right'caption='[[3n4p]], [[Resolution|resolution]] 2.15Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3n4p]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_herpesvirus_5_strain_Towne Human herpesvirus 5 strain Towne]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N4P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N4P FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n4p OCA], [https://pdbe.org/3n4p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n4p RCSB], [https://www.ebi.ac.uk/pdbsum/3n4p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n4p ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TRM3_HCMVA TRM3_HCMVA] Component of the molecular motor that translocates genomic DNA in empty capsid during DNA packaging. Heterodimerizes with small terminase protein to be docked on capsid portal protein. The latter forms a ring in which genomic DNA in translocated into the capsid. May have or induce an endonuclease activity to cleave the genome concatemer after encapsidation (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n4/3n4p_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3n4p ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Terminase 3D Structures|Terminase 3D Structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Human herpesvirus 5 strain Towne]] | |
| - | [[Category: Human herpesvirus 5]] | + | [[Category: Large Structures]] |
| - | [[Category: Arnan | + | [[Category: Arnan C]] |
| - | [[Category: Blanco | + | [[Category: Blanco AG]] |
| - | [[Category: Coll | + | [[Category: Coll M]] |
| - | [[Category: Hart | + | [[Category: Hart DJ]] |
| - | [[Category: Mas | + | [[Category: Mas PJ]] |
| - | [[Category: Nadal | + | [[Category: Nadal M]] |
| - | [[Category: Sola | + | [[Category: Sola M]] |
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Current revision
Human cytomegalovirus terminase nuclease domain
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