3n93
From Proteopedia
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| - | {{STRUCTURE_3n93| PDB=3n93 | SCENE= }} | ||
| - | ===Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 3=== | ||
| - | {{ABSTRACT_PUBMED_020966082}} | ||
| - | == | + | ==Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 3== |
| - | [[ | + | <StructureSection load='3n93' size='340' side='right'caption='[[3n93]], [[Resolution|resolution]] 2.50Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[3n93]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N93 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N93 FirstGlance]. <br> |
| - | [[3n93]] is a 3 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n93 OCA], [https://pdbe.org/3n93 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n93 RCSB], [https://www.ebi.ac.uk/pdbsum/3n93 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n93 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/UCN3_HUMAN UCN3_HUMAN] Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Pal K]] |
| - | + | [[Category: Pioszak AA]] | |
| - | [[Category: | + | [[Category: Swaminathan K]] |
| - | [[Category: | + | [[Category: Xu HE]] |
| - | [[Category: | + | |
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Current revision
Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 3
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