3n7n

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{{STRUCTURE_3n7n| PDB=3n7n | SCENE= }}
 
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===Structure of Csm1/Lrs4 complex===
 
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{{ABSTRACT_PUBMED_20723757}}
 
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==Function==
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==Structure of Csm1/Lrs4 complex==
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[[http://www.uniprot.org/uniprot/CSM1_YEAST CSM1_YEAST]] Component of the monopolin complex which promotes monoorientation during meiosis I, required for chromosome segregation during meiosis. Plays also a mitotic role in DNA replication.<ref>PMID:11470404</ref> <ref>PMID:12689592</ref> <ref>PMID:15023545</ref> <ref>PMID:16487579</ref> <ref>PMID:18997772</ref> [[http://www.uniprot.org/uniprot/LRS4_YEAST LRS4_YEAST]] Component of the monopolin complex which promotes monoorientation during meiosis I, required for chromosome segregation during meiosis. Involved in rDNA silencing.<ref>PMID:10082585</ref> <ref>PMID:12689592</ref> <ref>PMID:12586695</ref>
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<StructureSection load='3n7n' size='340' side='right'caption='[[3n7n]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[3n7n]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N7N FirstGlance]. <br>
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[[3n7n]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N7N OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n7n OCA], [https://pdbe.org/3n7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n7n RCSB], [https://www.ebi.ac.uk/pdbsum/3n7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n7n ProSAT]</span></td></tr>
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==Reference==
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</table>
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<ref group="xtra">PMID:020723757</ref><references group="xtra"/><references/>
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== Function ==
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[https://www.uniprot.org/uniprot/CSM1_YEAST CSM1_YEAST] Component of the monopolin complex which promotes monoorientation during meiosis I, required for chromosome segregation during meiosis. Plays also a mitotic role in DNA replication.<ref>PMID:11470404</ref> <ref>PMID:12689592</ref> <ref>PMID:15023545</ref> <ref>PMID:16487579</ref> <ref>PMID:18997772</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n7/3n7n_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3n7n ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Corbett, K D.]]
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[[Category: Corbett KD]]
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[[Category: Harrison, S C.]]
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[[Category: Harrison SC]]
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[[Category: Meiosis]]
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[[Category: Rdna]]
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[[Category: Replication]]
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Current revision

Structure of Csm1/Lrs4 complex

PDB ID 3n7n

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