2ew1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:40, 23 August 2023) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2ew1.gif|left|200px]]<br /><applet load="2ew1" size="350" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2ew1, resolution 2.00&Aring;" />
 
-
'''Crystal Structure of Rab30 in complex with a GTP analogue'''<br />
 
-
==About this Structure==
+
==Crystal Structure of Rab30 in complex with a GTP analogue==
-
2EW1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=GNP:'>GNP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EW1 OCA].
+
<StructureSection load='2ew1' size='340' side='right'caption='[[2ew1]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
[[Category: Homo sapiens]]
+
== Structural highlights ==
-
[[Category: Single protein]]
+
<table><tr><td colspan='2'>[[2ew1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EW1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EW1 FirstGlance]. <br>
-
[[Category: Arrowsmith, C H.]]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
[[Category: Bochkarev, A.]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
[[Category: Edwards, A M.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ew1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ew1 OCA], [https://pdbe.org/2ew1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ew1 RCSB], [https://www.ebi.ac.uk/pdbsum/2ew1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ew1 ProSAT]</span></td></tr>
-
[[Category: Ismail, S.]]
+
</table>
-
[[Category: Park, H W.]]
+
== Function ==
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[https://www.uniprot.org/uniprot/RAB30_HUMAN RAB30_HUMAN] The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). Required for maintaining the structural integrity of the Golgi apparatus, possibly by mediating interactions with cytoplasmic scaffolding proteins.
-
[[Category: Shen, Y.]]
+
== Evolutionary Conservation ==
-
[[Category: Sundstrom, M.]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Wang, J.]]
+
Check<jmol>
-
[[Category: GNP]]
+
<jmolCheckbox>
-
[[Category: MG]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/2ew1_consurf.spt"</scriptWhenChecked>
-
[[Category: g-protein]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: gtp analogue]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: rab]]
+
</jmolCheckbox>
-
[[Category: sgc]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ew1 ConSurf].
-
[[Category: structural genomics]]
+
<div style="clear:both"></div>
-
[[Category: structural genomics consortium]]
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:15:08 2008''
+
==See Also==
 +
*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Arrowsmith CH]]
 +
[[Category: Bochkarev A]]
 +
[[Category: Edwards AM]]
 +
[[Category: Ismail S]]
 +
[[Category: Park HW]]
 +
[[Category: Shen Y]]
 +
[[Category: Sundstrom M]]
 +
[[Category: Wang J]]

Current revision

Crystal Structure of Rab30 in complex with a GTP analogue

PDB ID 2ew1

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2ew1"
Personal tools