2f2e

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[[Image:2f2e.gif|left|200px]]<br /><applet load="2f2e" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2f2e, resolution 1.85&Aring;" />
 
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'''Crystal Structure of PA1607, a Putative Transcription Factor'''<br />
 
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==About this Structure==
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==Crystal Structure of PA1607, a Putative Transcription Factor==
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2F2E is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa] with <scene name='pdbligand=GLC:'>GLC</scene> and <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2E OCA].
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<StructureSection load='2f2e' size='340' side='right'caption='[[2f2e]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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[[Category: Pseudomonas aeruginosa]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[2f2e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F2E FirstGlance]. <br>
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[[Category: Cuff, M.]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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[[Category: Edwards, A.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Joachimiak, A.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2e OCA], [https://pdbe.org/2f2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f2e RCSB], [https://www.ebi.ac.uk/pdbsum/2f2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f2e ProSAT], [https://www.topsan.org/Proteins/MCSG/2f2e TOPSAN]</span></td></tr>
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[[Category: Lunin, V.]]
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</table>
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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== Function ==
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[[Category: Sanders, D A.R.]]
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[https://www.uniprot.org/uniprot/Q9I3B4_PSEAE Q9I3B4_PSEAE]
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[[Category: Savchenko, A.]]
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== Evolutionary Conservation ==
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[[Category: Sieminska, E A.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Xu, X.]]
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Check<jmol>
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[[Category: Zheng, H.]]
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<jmolCheckbox>
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[[Category: GLC]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f2/2f2e_consurf.spt"</scriptWhenChecked>
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[[Category: SO4]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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[[Category: apc5613]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: helix-trun-helix]]
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</jmolCheckbox>
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[[Category: mcsg]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f2e ConSurf].
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[[Category: midwest center for structural genomics]]
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<div style="clear:both"></div>
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[[Category: protein structure initiative]]
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<div style="background-color:#fffaf0;">
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[[Category: psi]]
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== Publication Abstract from PubMed ==
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[[Category: structural genomics]]
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The structure of the PA1607 protein from Pseudomonas aureginosa was determined at 1.85 A resolution using the Se-Met multiwavelength anomalous diffraction (MAD) technique. PA1607 forms a dimer and adopts a winged-helix motif similar to the MarR family of transcription regulators, though it has an unusual dimerization profile. The DNA-binding regions and a putative metal-binding site are not conserved in PA1607.
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[[Category: transcription factor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:16:59 2008''
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The X-ray crystal structure of PA1607 from Pseudomonas aureginosa at 1.9 A resolution--a putative transcription factor.,Sieminska EA, Xu X, Savchenko A, Sanders DA Protein Sci. 2007 Mar;16(3):543-9. PMID:17322537<ref>PMID:17322537</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 2f2e" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Pseudomonas aeruginosa]]
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[[Category: Cuff M]]
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[[Category: Edwards A]]
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[[Category: Joachimiak A]]
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[[Category: Lunin V]]
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[[Category: Sanders DA]]
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[[Category: Savchenko A]]
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[[Category: Sieminska EA]]
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[[Category: Xu X]]
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[[Category: Zheng H]]

Current revision

Crystal Structure of PA1607, a Putative Transcription Factor

PDB ID 2f2e

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