3w5j

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{{STRUCTURE_3w5j| PDB=3w5j | SCENE= }}
 
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===Crystal structure of GDP-bound NfeoB from Gallionella capsiferriformans===
 
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{{ABSTRACT_PUBMED_23545645}}
 
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==About this Structure==
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==Crystal structure of GDP-bound NfeoB from Gallionella capsiferriformans==
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[[3w5j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallionella_capsiferriformans_es-2 Gallionella capsiferriformans es-2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W5J OCA].
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<StructureSection load='3w5j' size='340' side='right'caption='[[3w5j]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
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[[Category: Gallionella capsiferriformans es-2]]
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== Structural highlights ==
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[[Category: Deshpande, C N.]]
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<table><tr><td colspan='2'>[[3w5j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallionella_capsiferriformans_ES-2 Gallionella capsiferriformans ES-2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W5J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W5J FirstGlance]. <br>
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[[Category: Jormakka, M.]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.932&#8491;</td></tr>
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[[Category: McGrath, A P.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: G protein]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w5j OCA], [https://pdbe.org/3w5j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w5j RCSB], [https://www.ebi.ac.uk/pdbsum/3w5j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w5j ProSAT]</span></td></tr>
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[[Category: Gdp]]
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</table>
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[[Category: Gtpase]]
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== Function ==
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[[Category: Iron transport]]
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[https://www.uniprot.org/uniprot/D9SIP4_GALCS D9SIP4_GALCS]
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[[Category: Metal transport]]
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<div style="background-color:#fffaf0;">
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[[Category: Transmembrane]]
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== Publication Abstract from PubMed ==
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FeoB is a transmembrane protein involved in ferrous iron uptake in prokaryotic organisms. FeoB comprises a cytoplasmic soluble domain termed NFeoB and a C-terminal polytopic transmembrane domain. Recent structures of NFeoB have revealed two structural subdomains: a canonical GTPase domain and a five-helix helical domain. The GTPase domain hydrolyses GTP to GDP through a well characterized mechanism, a process which is required for Fe(2+) transport. In contrast, the precise role of the helical domain has not yet been fully determined. Here, the structure of the cytoplasmic domain of FeoB from Gallionella capsiferriformans is reported. Unlike recent structures of NFeoB, the G. capsiferriformans NFeoB structure is highly unusual in that it does not contain a helical domain. The crystal structures of both apo and GDP-bound protein forms a domain-swapped dimer.
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Structure of an atypical FeoB G-domain reveals a putative domain-swapped dimer.,Deshpande CN, McGrath AP, Font J, Guilfoyle AP, Maher MJ, Jormakka M Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Apr 1;69(Pt 4):399-404., doi: 10.1107/S1744309113005939. Epub 2013 Mar 29. PMID:23545645<ref>PMID:23545645</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3w5j" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Gallionella capsiferriformans ES-2]]
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[[Category: Large Structures]]
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[[Category: Deshpande CN]]
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[[Category: Jormakka M]]
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[[Category: McGrath AP]]

Current revision

Crystal structure of GDP-bound NfeoB from Gallionella capsiferriformans

PDB ID 3w5j

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