2f7s
From Proteopedia
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| - | [[Image:2f7s.gif|left|200px]]<br /><applet load="2f7s" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2f7s, resolution 2.70Å" /> | ||
| - | '''The crystal structure of human Rab27b bound to GDP'''<br /> | ||
| - | == | + | ==The crystal structure of human Rab27b bound to GDP== |
| - | + | <StructureSection load='2f7s' size='340' side='right'caption='[[2f7s]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2f7s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F7S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F7S FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |
| - | [ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f7s OCA], [https://pdbe.org/2f7s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f7s RCSB], [https://www.ebi.ac.uk/pdbsum/2f7s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f7s ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/RB27B_HUMAN RB27B_HUMAN] May be involved in targeting uroplakins to urothelial apical membranes (By similarity). | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | [ | + | Check<jmol> |
| - | [[ | + | <jmolCheckbox> |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f7/2f7s_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | + | </jmolCheckbox> | |
| - | [ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f7s ConSurf]. |
| - | [[ | + | <div style="clear:both"></div> |
| - | [ | + | |
| - | + | ||
| - | + | ==See Also== | |
| + | *[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Bochkarev A]] | ||
| + | [[Category: Edwards AM]] | ||
| + | [[Category: Ismail S]] | ||
| + | [[Category: Park HW]] | ||
| + | [[Category: Shen Y]] | ||
| + | [[Category: Sundstrom M]] | ||
| + | [[Category: Tempel W]] | ||
| + | [[Category: Wang J]] | ||
Current revision
The crystal structure of human Rab27b bound to GDP
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bochkarev A | Edwards AM | Ismail S | Park HW | Shen Y | Sundstrom M | Tempel W | Wang J
