2fbl
From Proteopedia
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| - | [[Image:2fbl.gif|left|200px]]<br /><applet load="2fbl" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2fbl, resolution 1.90Å" /> | ||
| - | '''The crystal structure of the hypothetical protein NE1496'''<br /> | ||
| - | == | + | ==The crystal structure of the hypothetical protein NE1496== |
| - | + | <StructureSection load='2fbl' size='340' side='right'caption='[[2fbl]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2fbl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Nitrosomonas_europaea Nitrosomonas europaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FBL FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fbl OCA], [https://pdbe.org/2fbl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fbl RCSB], [https://www.ebi.ac.uk/pdbsum/2fbl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fbl ProSAT], [https://www.topsan.org/Proteins/MCSG/2fbl TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/3PASE_NITEU 3PASE_NITEU] Involved in the hydrolysis of the beta-gamma-phosphoanhydride linkage of triphosphate-containing substrates (inorganic or nucleoside-linked). Catalyzes the hydrolysis of inorganic triphosphate (PPPi). The enzyme has a strong preference for linear PPPi compared with cyclic PPPi (cyclic trimetaphosphate) and to the linear P4. The longer chains polyphosphate are not hydrolyzed. It has only a slight thiamine triphosphatase (ThTPase) activity. Nucleoside triphosphatase activity is negligible in the presence of magnesium, but a small activity is observed in the presence of manganese, in particular with GTP.<ref>PMID:21840996</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fb/2fbl_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fbl ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Nitrosomonas europaea]] | [[Category: Nitrosomonas europaea]] | ||
| - | + | [[Category: Binkowski TA]] | |
| - | [[Category: Binkowski | + | [[Category: Edwards AM]] |
| - | [[Category: Edwards | + | [[Category: Joachimiak A]] |
| - | [[Category: Joachimiak | + | [[Category: Lunin VV]] |
| - | [[Category: Lunin | + | [[Category: Onopriyenko O]] |
| - | + | [[Category: Savchenko A]] | |
| - | [[Category: Onopriyenko | + | [[Category: Skarina T]] |
| - | [[Category: Savchenko | + | |
| - | [[Category: Skarina | + | |
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Current revision
The crystal structure of the hypothetical protein NE1496
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