4ill
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| - | {{STRUCTURE_4ill| PDB=4ill | SCENE= }} | ||
| - | ===Recognition and Cleavage of a non-structured CRISPR RNA by its Processing Endoribonuclease Cas6=== | ||
| - | {{ABSTRACT_PUBMED_23454186}} | ||
| - | == | + | ==Recognition and Cleavage of a non-structured CRISPR RNA by its Processing Endoribonuclease Cas6== |
| - | [[4ill]] is a 4 chain structure with sequence from [ | + | <StructureSection load='4ill' size='340' side='right'caption='[[4ill]], [[Resolution|resolution]] 2.48Å' scene=''> |
| - | [[ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[4ill]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ILL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ILL FirstGlance]. <br> |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.484Å</td></tr> | |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ill FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ill OCA], [https://pdbe.org/4ill PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ill RCSB], [https://www.ebi.ac.uk/pdbsum/4ill PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ill ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/CAS6B_SACS2 CAS6B_SACS2] CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease, generating an 8 base-long tag known as the 5' handle.<ref>PMID:21507944</ref> |
| - | [[Category: | + | |
| - | [[Category: | + | ==See Also== |
| + | *[[CRISPR subtype I-A|CRISPR subtype I-A]] | ||
| + | *[[Endonuclease 3D structures|Endonuclease 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharolobus solfataricus P2]] | ||
| + | [[Category: Li H]] | ||
| + | [[Category: Shao Y]] | ||
Current revision
Recognition and Cleavage of a non-structured CRISPR RNA by its Processing Endoribonuclease Cas6
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