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1u22

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{{STRUCTURE_1u22| PDB=1u22 | SCENE= }}
 
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===A. thaliana cobalamine independent methionine synthase===
 
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{{ABSTRACT_PUBMED_15326182}}
 
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==Function==
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==A. thaliana cobalamine independent methionine synthase==
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[[http://www.uniprot.org/uniprot/METE_ARATH METE_ARATH]] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
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<StructureSection load='1u22' size='340' side='right'caption='[[1u22]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1u22]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U22 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HCS:2-AMINO-4-MERCAPTO-BUTYRIC+ACID'>HCS</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=THG:(6S)-5,6,7,8-TETRAHYDROFOLATE'>THG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u22 OCA], [https://pdbe.org/1u22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u22 RCSB], [https://www.ebi.ac.uk/pdbsum/1u22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u22 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/METE1_ARATH METE1_ARATH] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.<ref>PMID:15024005</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u2/1u22_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u22 ConSurf].
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<div style="clear:both"></div>
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==About this Structure==
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==See Also==
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[[1u22]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U22 OCA].
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*[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:015326182</ref><references group="xtra"/><references/>
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__TOC__
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[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]
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</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
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[[Category: Dumas, R.]]
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[[Category: Large Structures]]
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[[Category: Ferrer, J L.]]
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[[Category: Dumas R]]
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[[Category: Ravanel, S.]]
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[[Category: Ferrer J-L]]
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[[Category: Robert, M.]]
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[[Category: Ravanel S]]
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[[Category: Homocysteine]]
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[[Category: Robert M]]
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[[Category: Methionine]]
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[[Category: Methyltetrahydrofolate]]
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[[Category: Synthase]]
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[[Category: Transferase]]
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Current revision

A. thaliana cobalamine independent methionine synthase

PDB ID 1u22

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