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4isj
From Proteopedia
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| - | {{STRUCTURE_4isj| PDB=4isj | SCENE= }} | ||
| - | ===RNA Ligase RtcB in complex with Mn(II)=== | ||
| - | {{ABSTRACT_PUBMED_23560983}} | ||
| - | == | + | ==RNA Ligase RtcB in complex with Mn(II)== |
| - | [[http://www.uniprot.org/uniprot/RTCB_PYRHO RTCB_PYRHO | + | <StructureSection load='4isj' size='340' side='right'caption='[[4isj]], [[Resolution|resolution]] 2.34Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4isj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ISJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ISJ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.344Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PRD_900003:sucrose'>PRD_900003</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4isj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4isj OCA], [https://pdbe.org/4isj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4isj RCSB], [https://www.ebi.ac.uk/pdbsum/4isj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4isj ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RTCB_PYRHO RTCB_PYRHO] tRNA-splicing ligase that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as a RNA ligase with broad substrate specificity, and may function toward other RNAs (By similarity). | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[RNA ligase|RNA ligase]] |
| - | [[Category: Pyrococcus horikoshii | + | __TOC__ |
| - | [[Category: Bingman | + | </StructureSection> |
| - | [[Category: Desai | + | [[Category: Large Structures]] |
| - | [[Category: Phillips | + | [[Category: Pyrococcus horikoshii OT3]] |
| - | [[Category: Raines | + | [[Category: Bingman CA]] |
| - | + | [[Category: Desai KK]] | |
| - | + | [[Category: Phillips Jr GN]] | |
| + | [[Category: Raines RT]] | ||
Current revision
RNA Ligase RtcB in complex with Mn(II)
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