4k1o

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{{STRUCTURE_4k1o| PDB=4k1o | SCENE= }}
 
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===Crystal structure of the alphaN-catenin actin-binding domain===
 
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{{ABSTRACT_PUBMED_23589308}}
 
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==Function==
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==Crystal structure of the alphaN-catenin actin-binding domain==
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[[http://www.uniprot.org/uniprot/CTNA2_MOUSE CTNA2_MOUSE]] May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of startle modulation.<ref>PMID:12089526</ref> <ref>PMID:12123610</ref> <ref>PMID:15034585</ref>
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<StructureSection load='4k1o' size='340' side='right'caption='[[4k1o]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4k1o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K1O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K1O FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.603&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k1o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k1o OCA], [https://pdbe.org/4k1o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k1o RCSB], [https://www.ebi.ac.uk/pdbsum/4k1o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k1o ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CTNA2_MOUSE CTNA2_MOUSE] May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of startle modulation.<ref>PMID:12089526</ref> <ref>PMID:12123610</ref> <ref>PMID:15034585</ref>
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==About this Structure==
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==See Also==
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[[4k1o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K1O OCA].
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*[[Catenin 3D structures|Catenin 3D structures]]
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== References ==
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==Reference==
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<references/>
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<references group="xtra"/><references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Ikura, M.]]
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[[Category: Ikura M]]
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[[Category: Ishiyama, N.]]
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[[Category: Ishiyama N]]
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[[Category: Alpha-catenin]]
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[[Category: Cell adhesion]]
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[[Category: F-actin]]
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[[Category: Five-helix bundle]]
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Current revision

Crystal structure of the alphaN-catenin actin-binding domain

PDB ID 4k1o

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