2fj5
From Proteopedia
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- | [[Image:2fj5.gif|left|200px]]<br /><applet load="2fj5" size="350" color="white" frame="true" align="right" spinBox="true" | ||
- | caption="2fj5" /> | ||
- | '''SOLUTION STRUCTURE OF sole a-domain of HUMAN Metallothionein-3 (MT-3)'''<br /> | ||
- | == | + | ==SOLUTION STRUCTURE OF sole a-domain of HUMAN Metallothionein-3 (MT-3)== |
- | + | <StructureSection load='2fj5' size='340' side='right'caption='[[2fj5]]' scene=''> | |
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[2fj5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FJ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FJ5 FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fj5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fj5 OCA], [https://pdbe.org/2fj5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fj5 RCSB], [https://www.ebi.ac.uk/pdbsum/2fj5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fj5 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/MT3_HUMAN MT3_HUMAN] Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro. | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: Wu | + | [[Category: Wu H]] |
- | [[Category: Zhang | + | [[Category: Zhang Q]] |
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Current revision
SOLUTION STRUCTURE OF sole a-domain of HUMAN Metallothionein-3 (MT-3)
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