3osu

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{{STRUCTURE_3osu| PDB=3osu | SCENE= }}
 
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===Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, FabG, from Staphylococcus aureus===
 
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==Function==
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==Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, FabG, from Staphylococcus aureus==
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[[http://www.uniprot.org/uniprot/FABG_STAAM FABG_STAAM]] Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis (By similarity).
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<StructureSection load='3osu' size='340' side='right'caption='[[3osu]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3osu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OSU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OSU FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3osu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3osu OCA], [https://pdbe.org/3osu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3osu RCSB], [https://www.ebi.ac.uk/pdbsum/3osu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3osu ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FABG_STAAM FABG_STAAM] Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/os/3osu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3osu ConSurf].
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<div style="clear:both"></div>
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==About this Structure==
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==See Also==
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[[3osu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mu50 Staphylococcus aureus subsp. aureus mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OSU OCA].
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*[[Beta-ketoacyl carrier protein reductase 3D structures|Beta-ketoacyl carrier protein reductase 3D structures]]
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[[Category: Staphylococcus aureus subsp. aureus mu50]]
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__TOC__
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[[Category: Anderson, S M.]]
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</StructureSection>
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[[Category: Anderson, W F.]]
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[[Category: Large Structures]]
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Staphylococcus aureus subsp. aureus Mu50]]
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[[Category: Edwards, A.]]
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[[Category: Anderson SM]]
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[[Category: Onopriyenko, O.]]
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[[Category: Anderson WF]]
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[[Category: Savchenko, A.]]
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[[Category: Edwards A]]
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[[Category: Wawrzak, Z.]]
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[[Category: Onopriyenko O]]
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[[Category: Alpha and beta protein]]
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[[Category: Savchenko A]]
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[[Category: Center for structural genomics of infectious disease]]
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[[Category: Wawrzak Z]]
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[[Category: Csgid]]
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[[Category: Oxidoreductase]]
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[[Category: Structural genomic]]
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Current revision

Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, FabG, from Staphylococcus aureus

PDB ID 3osu

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