3opu
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| - | {{STRUCTURE_3opu| PDB=3opu | SCENE= }} | ||
| - | ===Crystal structure of the C-terminal domain of Streptococcus mutans surface protein SpaP=== | ||
| - | {{ABSTRACT_PUBMED_21206016}} | ||
| - | == | + | ==Crystal structure of the C-terminal domain of Streptococcus mutans surface protein SpaP== |
| - | [[3opu]] is a 6 chain structure with sequence from [ | + | <StructureSection load='3opu' size='340' side='right'caption='[[3opu]], [[Resolution|resolution]] 2.18Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3opu]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OPU FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.181Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3opu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3opu OCA], [https://pdbe.org/3opu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3opu RCSB], [https://www.ebi.ac.uk/pdbsum/3opu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3opu ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PAC_STRMG PAC_STRMG] Surface protein antigen implicated in dental caries. | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | SpaP is a 1500-residue adhesin expressed on the surface of the caries-implicated bacterium Streptococcus mutans. SpaP is a member of the antigen I/II (AgI/II) family of proteins expressed by oral streptococci. These surface proteins are crucial for the incorporation of streptococci into dental plaque. The structure of the C-terminal domain of SpaP (residues 1136-1489) was solved and refined to 2.2 A resolution with six molecules in the asymmetric unit. Similar to a related AgI/II structure, SpaP is stabilized by isopeptide bonds between lysine and asparagine side chains. | ||
| - | + | Structure of the C-terminal domain of the surface antigen SpaP from the caries pathogen Streptococcus mutans.,Nylander A, Forsgren N, Persson K Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Jan 1;67(Pt, 1):23-6. Epub 2010 Dec 21. PMID:21206016<ref>PMID:21206016</ref> | |
| - | <ref | + | |
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 3opu" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Streptococcus mutans]] | [[Category: Streptococcus mutans]] | ||
| - | [[Category: Nylander | + | [[Category: Nylander A]] |
| - | [[Category: Persson | + | [[Category: Persson K]] |
| - | + | ||
Current revision
Crystal structure of the C-terminal domain of Streptococcus mutans surface protein SpaP
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