2fxq

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[[Image:2fxq.gif|left|200px]]<br /><applet load="2fxq" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2fxq, resolution 1.85&Aring;" />
 
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'''Single-stranded DNA-binding protein from Thermus aquaticus'''<br />
 
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==Overview==
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==Single-stranded DNA-binding protein from Thermus aquaticus==
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The crystal structure of the single-stranded DNA-binding protein from Thermus aquaticus has been solved and refined at 1.85 A resolution. Two monomers, each encompassing two oligonucleotide/oligosaccharide-binding (OB) domains and a number of flexible beta-hairpin loops, form an oligomer of approximate D(2) symmetry typical of bacterial SSBs. Comparison with other SSB structures confirms considerable variability in the mode of oligomerization and aggregation of SSB oligomers.
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<StructureSection load='2fxq' size='340' side='right'caption='[[2fxq]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2fxq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FXQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FXQ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fxq OCA], [https://pdbe.org/2fxq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fxq RCSB], [https://www.ebi.ac.uk/pdbsum/2fxq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fxq ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SSB_THEAQ SSB_THEAQ]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fx/2fxq_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fxq ConSurf].
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<div style="clear:both"></div>
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==About this Structure==
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==See Also==
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2FXQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FXQ OCA].
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*[[Single-stranded DNA-binding protein 3D structures|Single-stranded DNA-binding protein 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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Structure of the single-stranded DNA-binding protein SSB from Thermus aquaticus., Jedrzejczak R, Dauter M, Dauter Z, Olszewski M, Dlugolecka A, Kur J, Acta Crystallogr D Biol Crystallogr. 2006 Nov;62(Pt 11):1407-12. Epub 2006, Oct 18. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17057346 17057346]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Thermus aquaticus]]
[[Category: Thermus aquaticus]]
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[[Category: Dauter, M.]]
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[[Category: Dauter M]]
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[[Category: Dauter, Z.]]
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[[Category: Dauter Z]]
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[[Category: Jedrzejczak, R.]]
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[[Category: Jedrzejczak R]]
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[[Category: 5 strand beta-sheet extended loops]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:26:09 2008''
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Current revision

Single-stranded DNA-binding protein from Thermus aquaticus

PDB ID 2fxq

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