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2g3v

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[[Image:2g3v.gif|left|200px]]<br /><applet load="2g3v" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2g3v, resolution 2.30&Aring;" />
 
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'''Crystal structure of CagS (HP0534, Cag13) from Helicobacter pylori'''<br />
 
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==Overview==
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==Crystal structure of CagS (HP0534, Cag13) from Helicobacter pylori==
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CagZ, a 23 kDa protein encoded by the cagZ gene (HP0526) of the cag pathogenicity island of Helicobacter pylori, has been cloned, over-expressed, purified and its three-dimensional structure determined. The protein consists of a single compact L-shaped domain, composed of seven alpha-helices including about 70% of the total residues. Three-dimensional homology searches did not reveal structural homologues, and CagZ can be considered representative of a new protein fold. The presence of a disordered C-terminal tail and the nature of the molecular surface suggest that CagZ may participate in the interaction of effector proteins with one or more components of the H.pylori type IV secretion system on the cytoplasmic side of the inner membrane.
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<StructureSection load='2g3v' size='340' side='right'caption='[[2g3v]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[2g3v]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G3V FirstGlance]. <br>
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2G3V is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3V OCA].
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g3v OCA], [https://pdbe.org/2g3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g3v RCSB], [https://www.ebi.ac.uk/pdbsum/2g3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g3v ProSAT]</span></td></tr>
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==Reference==
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</table>
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Crystal structure of CagZ, a protein from the Helicobacter pylori pathogenicity island that encodes for a type IV secretion system., Cendron L, Seydel A, Angelini A, Battistutta R, Zanotti G, J Mol Biol. 2004 Jul 16;340(4):881-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15223328 15223328]
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== Function ==
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[https://www.uniprot.org/uniprot/CAGS_HELPY CAGS_HELPY]
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__TOC__
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</StructureSection>
[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Angelini, A.]]
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[[Category: Angelini A]]
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[[Category: Battistutta, R.]]
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[[Category: Battistutta R]]
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[[Category: Cendron, L.]]
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[[Category: Cendron L]]
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[[Category: Montecucco, C.]]
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[[Category: Montecucco C]]
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[[Category: Seydel, A.]]
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[[Category: Seydel A]]
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[[Category: Tasca, E.]]
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[[Category: Tasca E]]
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[[Category: Zanotti, G.]]
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[[Category: Zanotti G]]
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[[Category: helicobacter pylori]]
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[[Category: pathogenicity island]]
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[[Category: type iv secretion system]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:27:56 2008''
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Current revision

Crystal structure of CagS (HP0534, Cag13) from Helicobacter pylori

PDB ID 2g3v

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