3j3t
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structural dynamics of the MecA-ClpC complex revealed by cryo-EM== | |
| - | + | <SX load='3j3t' size='340' side='right' viewer='molstar' caption='[[3j3t]], [[Resolution|resolution]] 9.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3j3t]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J3T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J3T FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 9Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j3t OCA], [https://pdbe.org/3j3t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j3t RCSB], [https://www.ebi.ac.uk/pdbsum/3j3t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j3t ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MECA1_BACSU MECA1_BACSU] Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.<ref>PMID:12598648</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </SX> | ||
| + | [[Category: Bacillus subtilis subsp. subtilis str. 168]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gao N]] | ||
| + | [[Category: Lei J]] | ||
| + | [[Category: Li N]] | ||
| + | [[Category: Liu J]] | ||
| + | [[Category: Mei Z]] | ||
| + | [[Category: Qi Y]] | ||
| + | [[Category: Shi Y]] | ||
| + | [[Category: Wang F]] | ||
| + | [[Category: Xu Y]] | ||
Current revision
Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
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Categories: Bacillus subtilis subsp. subtilis str. 168 | Large Structures | Gao N | Lei J | Li N | Liu J | Mei Z | Qi Y | Shi Y | Wang F | Xu Y
