4bl5
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4bl5 is ON HOLD Authors: Vollmar, M., Shafqat, N., Rojkova, A., Krojer, T., Bradley, A., Raynor, J.W., Kavanagh, K., von Delft, F., Arrowsmith, C.H....) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human GDP-L-fucose synthase with bound NADP and product GDP-L-fucose== | |
| - | + | <StructureSection load='4bl5' size='340' side='right'caption='[[4bl5]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4bl5]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BL5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BL5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GFB:GUANOSINE-5-DIPHOSPHATE-BETA-L-FUCOPYRANOSE'>GFB</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bl5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bl5 OCA], [https://pdbe.org/4bl5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bl5 RCSB], [https://www.ebi.ac.uk/pdbsum/4bl5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bl5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FCL_HUMAN FCL_HUMAN] Two step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Bountra C]] | ||
| + | [[Category: Bradley A]] | ||
| + | [[Category: Edwards A]] | ||
| + | [[Category: Kavanagh K]] | ||
| + | [[Category: Krojer T]] | ||
| + | [[Category: Oppermann U]] | ||
| + | [[Category: Raynor JW]] | ||
| + | [[Category: Rojkova A]] | ||
| + | [[Category: Shafqat N]] | ||
| + | [[Category: Vollmar M]] | ||
| + | [[Category: Yue WW]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
Crystal structure of human GDP-L-fucose synthase with bound NADP and product GDP-L-fucose
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Bradley A | Edwards A | Kavanagh K | Krojer T | Oppermann U | Raynor JW | Rojkova A | Shafqat N | Vollmar M | Yue WW | Von Delft F
